1 Janus Kinase (JAK) Inhibitors Market Overview 1.1 Product Overview and Scope of Janus Kinase (JAK) Inhibitors 1.2 Janus Kinase (JAK) Inhibitors Segment by Type 1.2.1 Global Janus Kinase (JAK) Inhibitors Sales Growth Rate Comparison by Type (2021-2027) 1.2.2 Autoimmune disorders 1.2.3 Oncology 1.3 Janus Kinase (JAK) Inhibitors Segment by Application 1.3.1 Janus Kinase (JAK) Inhibitors Sales Comparison by Application: (2021-2027) 1.3.2 Clinics 1.3.3 Hospitals 1.4 Global Janus Kinase (JAK) Inhibitors Market Size Estimates and Forecasts 1.4.1 Global Janus Kinase (JAK) Inhibitors Revenue 2016-2027 1.4.2 Global Janus Kinase (JAK) Inhibitors Sales 2016-2027 1.4.3 Janus Kinase (JAK) Inhibitors Market Size by Region: 2016 Versus 2021 Versus 2027 2 Janus Kinase (JAK) Inhibitors Market Competition by Manufacturers 2.1 Global Janus Kinase (JAK) Inhibitors Sales Market Share by Manufacturers (2016-2021) 2.2 Global Janus Kinase (JAK) Inhibitors Revenue Market Share by Manufacturers (2016-2021) 2.3 Global Janus Kinase (JAK) Inhibitors Average Price by Manufacturers (2016-2021) 2.4 Manufacturers Janus Kinase (JAK) Inhibitors Manufacturing Sites, Area Served, Product Type 2.5 Janus Kinase (JAK) Inhibitors Market Competitive Situation and Trends 2.5.1 Janus Kinase (JAK) Inhibitors Market Concentration Rate 2.5.2 The Global Top 5 and Top 10 Largest Janus Kinase (JAK) Inhibitors Players Market Share by Revenue 2.5.3 Global Janus Kinase (JAK) Inhibitors Market Share by Company Type (Tier 1, Tier 2 and Tier 3) 2.6 Manufacturers Mergers & Acquisitions, Expansion Plans 3 Janus Kinase (JAK) Inhibitors Retrospective Market Scenario by Region 3.1 Global Janus Kinase (JAK) Inhibitors Retrospective Market Scenario in Revenue by Region: 2016-2021 3.2 Global Janus Kinase (JAK) Inhibitors Retrospective Market Scenario in Sales by Region: 2016-2021 3.3 North America Janus Kinase (JAK) Inhibitors Market Facts & Figures by Country 3.3.1 North America Janus Kinase (JAK) Inhibitors Sales by Country 3.3.2 North America Janus Kinase (JAK) Inhibitors Revenue by Country 3.3.3 U.S. 3.3.4 Canada 3.4 Europe Janus Kinase (JAK) Inhibitors Market Facts & Figures by Country 3.4.1 Europe Janus Kinase (JAK) Inhibitors Sales by Country 3.4.2 Europe Janus Kinase (JAK) Inhibitors Revenue by Country 3.4.3 Germany 3.4.4 France 3.4.5 U.K. 3.4.6 Italy 3.4.7 Russia 3.5 Asia Pacific Janus Kinase (JAK) Inhibitors Market Facts & Figures by Region 3.5.1 Asia Pacific Janus Kinase (JAK) Inhibitors Sales by Region 3.5.2 Asia Pacific Janus Kinase (JAK) Inhibitors Revenue by Region 3.5.3 China 3.5.4 Japan 3.5.5 South Korea 3.5.6 India 3.5.7 Australia 3.5.8 Taiwan 3.5.9 Indonesia 3.5.10 Thailand 3.5.11 Malaysia 3.5.12 Philippines 3.5.13 Vietnam 3.6 Latin America Janus Kinase (JAK) Inhibitors Market Facts & Figures by Country 3.6.1 Latin America Janus Kinase (JAK) Inhibitors Sales by Country 3.6.2 Latin America Janus Kinase (JAK) Inhibitors Revenue by Country 3.6.3 Mexico 3.6.4 Brazil 3.6.5 Argentina 3.7 Middle East and Africa Janus Kinase (JAK) Inhibitors Market Facts & Figures by Country 3.7.1 Middle East and Africa Janus Kinase (JAK) Inhibitors Sales by Country 3.7.2 Middle East and Africa Janus Kinase (JAK) Inhibitors Revenue by Country 3.7.3 Turkey 3.7.4 Saudi Arabia 3.7.5 U.A.E 4 Global Janus Kinase (JAK) Inhibitors Historic Market Analysis by Type 4.1 Global Janus Kinase (JAK) Inhibitors Sales Market Share by Type (2016-2021) 4.2 Global Janus Kinase (JAK) Inhibitors Revenue Market Share by Type (2016-2021) 4.3 Global Janus Kinase (JAK) Inhibitors Price by Type (2016-2021) 5 Global Janus Kinase (JAK) Inhibitors Historic Market Analysis by Application 5.1 Global Janus Kinase (JAK) Inhibitors Sales Market Share by Application (2016-2021) 5.2 Global Janus Kinase (JAK) Inhibitors Revenue Market Share by Application (2016-2021) 5.3 Global Janus Kinase (JAK) Inhibitors Price by Application (2016-2021) 6 Key Companies Profiled 6.1 Astellas Pharma, Inc. 6.1.1 Astellas Pharma, Inc. Corporation Information 6.1.2 Astellas Pharma, Inc. Description and Business Overview 6.1.3 Astellas Pharma, Inc. Janus Kinase (JAK) Inhibitors Sales, Revenue and Gross Margin (2016-2021) 6.1.4 Astellas Pharma, Inc. Product Portfolio 6.1.5 Astellas Pharma, Inc. Recent Developments/Updates 6.2 Eli Lilly and Co. 6.2.1 Eli Lilly and Co. Corporation Information 6.2.2 Eli Lilly and Co. Description and Business Overview 6.2.3 Eli Lilly and Co. Janus Kinase (JAK) Inhibitors Sales, Revenue and Gross Margin (2016-2021) 6.2.4 Eli Lilly and Co. Product Portfolio 6.2.5 Eli Lilly and Co. Recent Developments/Updates 6.3 Incyte Corp. 6.3.1 Incyte Corp. Corporation Information 6.3.2 Incyte Corp. Description and Business Overview 6.3.3 Incyte Corp. Janus Kinase (JAK) Inhibitors Sales, Revenue and Gross Margin (2016-2021) 6.3.4 Incyte Corp. Product Portfolio 6.3.5 Incyte Corp. Recent Developments/Updates 6.4 Novartis AG 6.4.1 Novartis AG Corporation Information 6.4.2 Novartis AG Description and Business Overview 6.4.3 Novartis AG Janus Kinase (JAK) Inhibitors Sales, Revenue and Gross Margin (2016-2021) 6.4.4 Novartis AG Product Portfolio 6.4.5 Novartis AG Recent Developments/Updates 6.5 Pfizer Inc. 6.5.1 Pfizer Inc. Corporation Information 6.5.2 Pfizer Inc. Description and Business Overview 6.5.3 Pfizer Inc. Janus Kinase (JAK) Inhibitors Sales, Revenue and Gross Margin (2016-2021) 6.5.4 Pfizer Inc. Product Portfolio 6.5.5 Pfizer Inc. Recent Developments/Updates 7 Janus Kinase (JAK) Inhibitors Manufacturing Cost Analysis 7.1 Janus Kinase (JAK) Inhibitors Key Raw Materials Analysis 7.1.1 Key Raw Materials 7.1.2 Key Suppliers of Raw Materials 7.2 Proportion of Manufacturing Cost Structure 7.3 Manufacturing Process Analysis of Janus Kinase (JAK) Inhibitors 7.4 Janus Kinase (JAK) Inhibitors Industrial Chain Analysis 8 Marketing Channel, Distributors and Customers 8.1 Marketing Channel 8.2 Janus Kinase (JAK) Inhibitors Distributors List 8.3 Janus Kinase (JAK) Inhibitors Customers 9 Janus Kinase (JAK) Inhibitors Market Dynamics 9.1 Janus Kinase (JAK) Inhibitors Industry Trends 9.2 Janus Kinase (JAK) Inhibitors Growth Drivers 9.3 Janus Kinase (JAK) Inhibitors Market Challenges 9.4 Janus Kinase (JAK) Inhibitors Market Restraints 10 Global Market Forecast 10.1 Janus Kinase (JAK) Inhibitors Market Estimates and Projections by Type 10.1.1 Global Forecasted Sales of Janus Kinase (JAK) Inhibitors by Type (2022-2027) 10.1.2 Global Forecasted Revenue of Janus Kinase (JAK) Inhibitors by Type (2022-2027) 10.2 Janus Kinase (JAK) Inhibitors Market Estimates and Projections by Application 10.2.1 Global Forecasted Sales of Janus Kinase (JAK) Inhibitors by Application (2022-2027) 10.2.2 Global Forecasted Revenue of Janus Kinase (JAK) Inhibitors by Application (2022-2027) 10.3 Janus Kinase (JAK) Inhibitors Market Estimates and Projections by Region 10.3.1 Global Forecasted Sales of Janus Kinase (JAK) Inhibitors by Region (2022-2027) 10.3.2 Global Forecasted Revenue of Janus Kinase (JAK) Inhibitors by Region (2022-2027) 11 Research Finding and Conclusion 12 Methodology and Data Source 12.1 Methodology/Research Approach 12.1.1 Research Programs/Design 12.1.2 Market Size Estimation 12.1.3 Market Breakdown and Data Triangulation 12.2 Data Source 12.2.1 Secondary Sources 12.2.2 Primary Sources 12.3 Author List 12.4 Disclaimer

List of Tables Table 1. Global Janus Kinase (JAK) Inhibitors Sales (K Units) Growth Rate Comparison by Type (2021-2027) Table 2. Global Janus Kinase (JAK) Inhibitors Sales (K Units) Comparison by Application (2021-2027) Table 3. Global Janus Kinase (JAK) Inhibitors Market Size by Region (US$ Million) (2016 VS 2021 VS 2027) Table 4. Key Manufacturers Janus Kinase (JAK) Inhibitors Covered in This Study Table 5. Global Janus Kinase (JAK) Inhibitors Sales (K Units) of Key Manufacturers (2016-2021) Table 6. Global Janus Kinase (JAK) Inhibitors Sales Share by Manufacturers (2016-2021) Table 7. Global Janus Kinase (JAK) Inhibitors Revenue (US$ Million) by Manufacturers (2016-2021) Table 8. Global Janus Kinase (JAK) Inhibitors Revenue Share by Manufacturers (2016-2021) Table 9. Global Market Janus Kinase (JAK) Inhibitors Average Price (USD/Unit) of Key Manufacturers (2016-2021) Table 10. Manufacturers Janus Kinase (JAK) Inhibitors Manufacturing Sites and Area Served Table 11. Manufacturers Janus Kinase (JAK) Inhibitors Product Type Table 12. Global Janus Kinase (JAK) Inhibitors Manufacturers Market Concentration Ratio (CR5 and HHI) Table 13. Global Janus Kinase (JAK) Inhibitors by Company Type (Tier 1, Tier 2 and Tier 3) (based on the Revenue in Janus Kinase (JAK) Inhibitors as of 2020) Table 14. Manufacturers Mergers & Acquisitions, Expansion Plans Table 15. Global Janus Kinase (JAK) Inhibitors Sales by Region (2016-2021) & (K Units) Table 16. Global Janus Kinase (JAK) Inhibitors Sales Market Share by Region (2016-2021) Table 17. Global Janus Kinase (JAK) Inhibitors Revenue by Region (2016-2021) & (US$ Million) Table 18. North America Janus Kinase (JAK) Inhibitors Sales by Country (2016-2021) & (K Units) Table 19. North America Janus Kinase (JAK) Inhibitors Sales Market Share by Country (2016-2021) Table 20. North America Janus Kinase (JAK) Inhibitors Revenue by Country (2016-2021) & (US$ Million) Table 21. North America Janus Kinase (JAK) Inhibitors Revenue Market Share by Country (2016-2021) Table 22. Europe Janus Kinase (JAK) Inhibitors Sales by Country (2016-2021) & (K Units) Table 23. Europe Janus Kinase (JAK) Inhibitors Sales Market Share by Country (2016-2021) Table 24. Europe Janus Kinase (JAK) Inhibitors Revenue by Country (2016-2021) & (US$ Million) Table 25. Europe Janus Kinase (JAK) Inhibitors Revenue Market Share by Country (2016-2021) Table 26. Asia Pacific Janus Kinase (JAK) Inhibitors Sales by Region (2016-2021) & (K Units) Table 27. Asia Pacific Janus Kinase (JAK) Inhibitors Sales Market Share by Region (2016-2021) Table 28. Asia Pacific Janus Kinase (JAK) Inhibitors Revenue by Region (2016-2021) & (US$ Million) Table 29. Asia Pacific Janus Kinase (JAK) Inhibitors Revenue Market Share by Region (2016-2021) Table 30. Latin America Janus Kinase (JAK) Inhibitors Sales by Country (2016-2021) & (K Units) Table 31. Latin America Janus Kinase (JAK) Inhibitors Sales Market Share by Country (2016-2021) Table 32. Latin America Janus Kinase (JAK) Inhibitors Revenue by Country (2016-2021) & (US$ Million) Table 33. Latin America Janus Kinase (JAK) Inhibitors Revenue Market Share by Country (2016-2021) Table 34. Middle East and Africa Janus Kinase (JAK) Inhibitors Sales by Country (2016-2021) & (K Units) Table 35. Middle East and Africa Janus Kinase (JAK) Inhibitors Sales Market Share by Country (2016-2021) Table 36. Middle East and Africa Janus Kinase (JAK) Inhibitors Revenue by Country (2016-2021) & (US$ Million) Table 37. Middle East and Africa Janus Kinase (JAK) Inhibitors Revenue Market Share by Country (2016-2021) Table 38. Global Janus Kinase (JAK) Inhibitors Sales (K Units) by Type (2016-2021) Table 39. Global Janus Kinase (JAK) Inhibitors Sales Market Share by Type (2016-2021) Table 40. Global Janus Kinase (JAK) Inhibitors Revenue (Million US$) by Type (2016-2021) Table 41. Global Janus Kinase (JAK) Inhibitors Revenue Share by Type (2016-2021) Table 42. Global Janus Kinase (JAK) Inhibitors Price (USD/Unit) by Type (2016-2021) Table 43. Global Janus Kinase (JAK) Inhibitors Sales (K Units) by Application (2016-2021) Table 44. Global Janus Kinase (JAK) Inhibitors Sales Market Share by Application (2016-2021) Table 45. Global Janus Kinase (JAK) Inhibitors Revenue (Million US$) by Application (2016-2021) Table 46. Global Janus Kinase (JAK) Inhibitors Revenue Share by Application (2016-2021) Table 47. Global Janus Kinase (JAK) Inhibitors Price (USD/Unit) by Application (2016-2021) Table 48. Astellas Pharma, Inc. Corporation Information Table 49. Astellas Pharma, Inc. Description and Business Overview Table 50. Astellas Pharma, Inc. Janus Kinase (JAK) Inhibitors Sales (K Units), Revenue (Million US$), Price (USD/Unit) and Gross Margin (2016-2021) Table 51. Astellas Pharma, Inc. Janus Kinase (JAK) Inhibitors Product Table 52. Astellas Pharma, Inc. Recent Developments/Updates Table 53. Eli Lilly and Co. Corporation Information Table 54. Eli Lilly and Co. Description and Business Overview Table 55. Eli Lilly and Co. Janus Kinase (JAK) Inhibitors Sales (K Units), Revenue (Million US$), Price (USD/Unit) and Gross Margin (2016-2021) Table 56. Eli Lilly and Co. Janus Kinase (JAK) Inhibitors Product Table 57. Eli Lilly and Co. Recent Developments/Updates Table 58. Incyte Corp. Corporation Information Table 59. Incyte Corp. Description and Business Overview Table 60. Incyte Corp. Janus Kinase (JAK) Inhibitors Sales (K Units), Revenue (Million US$), Price (USD/Unit) and Gross Margin (2016-2021) Table 61. Incyte Corp. Janus Kinase (JAK) Inhibitors Product Table 62. Incyte Corp. Recent Developments/Updates Table 63. Novartis AG Corporation Information Table 64. Novartis AG Description and Business Overview Table 65. Novartis AG Janus Kinase (JAK) Inhibitors Sales (K Units), Revenue (Million US$), Price (USD/Unit) and Gross Margin (2016-2021) Table 66. Novartis AG Janus Kinase (JAK) Inhibitors Product Table 67. Novartis AG Recent Developments/Updates Table 68. Pfizer Inc. Corporation Information Table 69. Pfizer Inc. Description and Business Overview Table 70. Pfizer Inc. Janus Kinase (JAK) Inhibitors Sales (K Units), Revenue (Million US$), Price (USD/Unit) and Gross Margin (2016-2021) Table 71. Pfizer Inc. Janus Kinase (JAK) Inhibitors Product Table 72. Pfizer Inc. Recent Developments/Updates Table 73. Production Base and Market Concentration Rate of Raw Material Table 74. Key Suppliers of Raw Materials Table 75. Janus Kinase (JAK) Inhibitors Distributors List Table 76. Janus Kinase (JAK) Inhibitors Customers List Table 77. Janus Kinase (JAK) Inhibitors Market Trends Table 78. Janus Kinase (JAK) Inhibitors Growth Drivers Table 79. Janus Kinase (JAK) Inhibitors Market Restraints Table 80. Global Janus Kinase (JAK) Inhibitors Sales Forecast by Type (2022-2027) & (K Units) Table 81. Global Janus Kinase (JAK) Inhibitors Sales Market Share Forecast by Type (2022-2027) Table 82. Global Janus Kinase (JAK) Inhibitors Revenue Forecast by Type (2022-2027) & (US$ Million) Table 83. Global Janus Kinase (JAK) Inhibitors Revenue Market Share Forecast by Type (2022-2027) Table 84. Global Janus Kinase (JAK) Inhibitors Sales Forecast by Application (2022-2027) & (K Units) Table 85. Global Janus Kinase (JAK) Inhibitors Sales Market Share Forecast by Application (2022-2027) Table 86. Global Janus Kinase (JAK) Inhibitors Revenue Forecast by Application (2022-2027) & (US$ Million) Table 87. Global Janus Kinase (JAK) Inhibitors Revenue Market Share Forecast by Application (2022-2027) Table 88. Global Janus Kinase (JAK) Inhibitors Sales Forecast by Region (2022-2027) & (K Units) Table 89. Global Janus Kinase (JAK) Inhibitors Sales Market Share Forecast by Region (2022-2027) Table 90. Global Janus Kinase (JAK) Inhibitors Revenue Forecast by Region (2022-2027) & (US$ Million) Table 91. Global Janus Kinase (JAK) Inhibitors Revenue Market Share Forecast by Region (2022-2027) Table 92. Research Programs/Design for This Report Table 93. Key Data Information from Secondary Sources Table 94. Key Data Information from Primary Sources List of Figures Figure 1. Product Picture of Janus Kinase (JAK) Inhibitors Figure 2. Global Janus Kinase (JAK) Inhibitors Market Share by Type in 2020 & 2027 Figure 3. Autoimmune disorders Product Picture Figure 4. Oncology Product Picture Figure 5. Global Janus Kinase (JAK) Inhibitors Market Share by Application in 2020 & 2027 Figure 6. Clinics Figure 7. Hospitals Figure 8. Global Janus Kinase (JAK) Inhibitors Revenue, (US$ Million), 2016 VS 2021 VS 2027 Figure 9. Global Janus Kinase (JAK) Inhibitors Market Size 2016-2027 (US$ Million) Figure 10. Global Janus Kinase (JAK) Inhibitors Sales 2016-2027 (K Units) Figure 11. Global Janus Kinase (JAK) Inhibitors Market Size Market Share by Region: 2016 VS 20210 VS 2027 Figure 12. Janus Kinase (JAK) Inhibitors Sales Share by Manufacturers in 2020 Figure 13. Global Janus Kinase (JAK) Inhibitors Revenue Share by Manufacturers in 2020 Figure 14. The Global 5 and 10 Largest Janus Kinase (JAK) Inhibitors Players: Market Share by Revenue in 2020 Figure 15. Janus Kinase (JAK) Inhibitors Market Share by Company Type (Tier 1, Tier 2 and Tier 3): 2016 VS 2021 Figure 16. Global Janus Kinase (JAK) Inhibitors Sales Market Share by Region (2016-2021) Figure 17. Global Janus Kinase (JAK) Inhibitors Sales Market Share by Region in 2020 Figure 18. Global Janus Kinase (JAK) Inhibitors Revenue Market Share by Region (2016-2021) Figure 19. Global Janus Kinase (JAK) Inhibitors Revenue Market Share by Region in 2020 Figure 20. U.S. Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 21. Canada Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 22. Germany Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 23. France Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 24. U.K. Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 25. Italy Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 26. Russia Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 27. China Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 28. Japan Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 29. South Korea Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 30. India Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 31. Australia Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 32. Taiwan Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 33. Indonesia Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 34. Thailand Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 35. Malaysia Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 36. Philippines Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 37. Vietnam Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 38. Mexico Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 39. Brazil Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 40. Argentina Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 41. Turkey Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 42. Saudi Arabia Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 43. U.A.E Janus Kinase (JAK) Inhibitors Revenue Growth Rate (2016-2021) (US$ Million) Figure 44. Sales Market Share of Janus Kinase (JAK) Inhibitors by Type (2016-2021) Figure 45. Sales Market Share of Janus Kinase (JAK) Inhibitors by Application (2016-2021) Figure 46. Sales Market Share of Janus Kinase (JAK) Inhibitors by Application in 2020 Figure 47. Revenue Share of Janus Kinase (JAK) Inhibitors by Application (2016-2021) Figure 48. Revenue Share of Janus Kinase (JAK) Inhibitors by Application in 2020 Figure 49. Manufacturing Cost Structure of Janus Kinase (JAK) Inhibitors Figure 50. Manufacturing Process Analysis of Janus Kinase (JAK) Inhibitors Figure 51. Janus Kinase (JAK) Inhibitors Industrial Chain Analysis Figure 52. Channels of Distribution Figure 53. Distributors Profiles Figure 54. Bottom-up and Top-down Approaches for This Report Figure 55. Data Triangulation Figure 56. Key Executives Interviewed

Astellas Pharma, Inc. Eli Lilly and Co. Incyte Corp. Novartis AG Pfizer Inc.