TABLE OF CONTENTS 1 INDUSTRY OVERVIEW 1.1 Opioid-induced Constipation Industry 1.1.1 Opioid-induced Constipation Overview 1.1.2 Terminology Definition in the Report 1.1.2.1 Capacity 1.1.2.2 Sales Volume 1.1.2.3 Sales Revenue 1.1.2.4 Ex-factory Price & Sales Price 1.1.2.5 Cost 1.1.2.6 Gross Margin 1.2 Products & Services Overview Scope 1.3 Opioid-induced Constipation in the Industry Chain 1.4 Industry Dynamics & Regulations 1.5 Global Market Overview 2 UPSTREAM & MANUFACTURING 2.1 Raw Materials / Components 2.2 Procurement Methods & Channels 2.3 Cost Structure & Manufacturing 2.4 Industry Capacity Overview 2.5 Production Distribution by Geography 2.5.1 Production in Major Regions / Countries 2.5.2 Trade Flow Overview 3 PRODUCT SEGMENT 3.1 Product Segmentation Market (2017 to 2021E) 3.1.1 Solid Market 3.1.2 Liquid Market 3.2 Market Status 4 APPLICATION / END-USE SEGMENT 4.1 Application Segmentation Market (2016 to 2021E) 4.1.1 Drugstore Market 4.1.2 Hospital Market 4.1.3 Others Market 4.2 Market Status 5 NORTH AMERICA 5.1 North America Market Growth 5.2 North America Market by Countries 5.3 Major Countries Market Growth 5.3.1 United States Market Size and Growth (2016-2021E) 5.3.2 Canada Market Size and Growth (2016-2021E) 5.3.3 Mexico Market Size and Growth (2016-2021E) 6 EUROPE 6.1 Europe Market Growth 6.2 Europe Market by Countries 6.3 Major Countries Market Growth 6.3.1 Germany Market Size and Growth (2016-2021E) 6.3.2 UK Market Size and Growth (2016-2021E) 6.3.3 France Market Size and Growth (2016-2021E) 6.3.4 Russia Market Size and Growth (2016-2021E) 6.3.5 Italy Market Size and Growth (2016-2021E) 6.3.6 Rest of Europe Market Size and Growth (2016-2021E) 7 ASIA-PACIFIC 7.1 ASIA-PACIFIC Market Growth 7.2 ASIA-PACIFIC Market by Countries 7.3 Major Countries Market Growth 7.3.1 China Market Size and Growth (2016-2021E) 7.3.2 India Market Size and Growth (2016-2021E) 7.3.3 Japan Market Size and Growth (2016-2021E) 7.3.4 South Korea Market Size and Growth (2016-2021E) 7.3.5 Southeast Asia Market Size and Growth (2016-2021E) 7.3.6 Australia Market Size and Growth (2016-2021E) 7.3.7 Rest of Asia Pacific Market Size and Growth (2016-2021E) 8 SOUTH AMERICA 8.1 South America Market Growth 8.2 South America Market by Countries 8.3 Major Countries Market Growth 8.3.1 Brazil Market Size and Growth (2016-2021E) 8.3.2 Argentina Market Size and Growth (2016-2021E) 8.3.3 Rest of South America Market Size and Growth (2016-2021E) 9 MIDDLE EAST & AFRICA 9.1 Middle East and Africa Market Growth 9.2 Middle East and Africa Market by Countries 9.3 Major Countries Market Growth 9.3.1 GCC Market Size and Growth (2016-2021E) 9.3.2 North Africa Market Size and Growth (2016-2021E) 9.3.3 South Africa Market Size and Growth (2016-2021E) 9.3.4 Rest of Middle East & Africa Market Size and Growth (2016-2021E) 10 MARKET FORECAST 10.1 Global Market Forecast Overview 10.2 Global Market Forecast by Type 10.3 Global Market Forecast by Application / End-Use 10.4 Global Market Forecast by Region 11 COMPETITION OF MAJOR PLAYERS 11.1 AstraZeneca (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.1.1 AstraZeneca Profile 11.1.2 AstraZeneca Products & Services Overview 11.1.3 AstraZeneca Main Business 11.1.4 AstraZeneca Business Operation 11.2 Takeda Pharmaceutical (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.2.1 Takeda Pharmaceutical Profile 11.2.2 Takeda Pharmaceutical Products & Services 11.2.3 Takeda Pharmaceutical Main Business 11.2.4 Takeda Pharmaceutical Business Operation 11.3 Valeant Pharmaceuticals International (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.3.1 Valeant Pharmaceuticals International Profile 11.3.2 Valeant Pharmaceuticals International Products & Services 11.3.3 Valeant Pharmaceuticals International Main Business 11.3.4 Valeant Pharmaceuticals International Business Operation 11.4 Abbott (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.4.1 Abbott Profile 11.4.2 Abbott Products & Services 11.4.3 Abbott Main Business 11.4.4 Abbott Business Operation 11.5 Bayer (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.5.1 Bayer Profile 11.5.2 Bayer Products & Services 11.5.3 Bayer Main Business 11.5.4 Bayer Business Operation 11.6 Boehringer Ingelheim (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.6.1 Boehringer Ingelheim Profile 11.6.2 Boehringer Ingelheim Products & Services 11.6.3 Boehringer Ingelheim Main Business 11.6.4 Boehringer Ingelheim Business Operation 11.7 C.B. Fleet (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.7.1 C.B. Fleet Profile 11.7.2 C.B. Fleet Products & Services 11.7.3 C.B. Fleet Main Business 11.7.4 C.B. Fleet Business Operation 11.8 Cosmo Pharmaceuticals (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.8.1 Cosmo Pharmaceuticals Profile 11.8.2 Cosmo Pharmaceuticals Products & Services 11.8.3 Cosmo Pharmaceuticals Main Business 11.8.4 Cosmo Pharmaceuticals Business Operation 11.9 Daewoong (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.9.1 Daewoong Profile 11.9.2 Daewoong Products & Services 11.9.3 Daewoong Main Business 11.9.4 Daewoong Business Operation 11.10 Daiichi Sankyo (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.10.1 Daiichi Sankyo Profile 11.10.2 Daiichi Sankyo Products & Services 11.10.3 Daiichi Sankyo Main Business 11.10.4 Daiichi Sankyo Business Operation 11.11 GlaxoSmithKline (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.11.1 GlaxoSmithKline Profile 11.11.2 GlaxoSmithKline Products & Services 11.11.3 GlaxoSmithKline Main Business 11.11.4 GlaxoSmithKline Business Operation 11.12 Ironwood Pharmaceuticals (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.12.1 Ironwood Pharmaceuticals Profile 11.12.2 Ironwood Pharmaceuticals Products & Services 11.12.3 Ironwood Pharmaceuticals Main Business 11.12.4 Ironwood Pharmaceuticals Business Operation 11.13 Johnson & Johnson (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.13.1 Johnson & Johnson Profile 11.13.2 Johnson & Johnson Products & Services 11.13.3 Johnson & Johnson Main Business 11.13.4 Johnson & Johnson Business Operation 11.14 Merck (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.14.1 Merck Profile 11.14.2 Merck Products & Services 11.14.3 Merck Main Business 11.14.4 Merck Business Operation 11.15 Mundipharma (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.15.1 Mundipharma Profile 11.15.2 Mundipharma Products & Services 11.15.3 Mundipharma Main Business 11.15.4 Mundipharma Business Operation 11.16 Nektar Therapeutics (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.16.1 Nektar Therapeutics Profile 11.16.2 Nektar Therapeutics Products & Services 11.16.3 Nektar Therapeutics Main Business 11.16.4 Nektar Therapeutics Business Operation 11.17 Pfizer (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.17.1 Pfizer Profile 11.17.2 Pfizer Products & Services 11.17.3 Pfizer Main Business 11.17.4 Pfizer Business Operation 11.18 Progenics Pharmaceuticals (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.18.1 Progenics Pharmaceuticals Profile 11.18.2 Progenics Pharmaceuticals Products & Services 11.18.3 Progenics Pharmaceuticals Main Business 11.18.4 Progenics Pharmaceuticals Business Operation 11.19 Shionogi (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.19.1 Shionogi Profile 11.19.2 Shionogi Products & Services 11.19.3 Shionogi Main Business 11.19.4 Shionogi Business Operation 11.20 SLA Pharma (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.20.1 SLA Pharma Profile 11.20.2 SLA Pharma Products & Services 11.20.3 SLA Pharma Main Business 11.20.4 SLA Pharma Business Operation 11.21 Sucampo (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.21.1 Sucampo Profile 11.21.2 Sucampo Products & Services 11.21.3 Sucampo Main Business 11.21.4 Sucampo Business Operation 11.22 Synergy Pharmaceuticals (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.22.1 Synergy Pharmaceuticals Profile 11.22.2 Synergy Pharmaceuticals Products & Services 11.22.3 Synergy Pharmaceuticals Main Business 11.22.4 Synergy Pharmaceuticals Business Operation 11.23 Theravance (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.23.1 Theravance Profile 11.23.2 Theravance Products & Services 11.23.3 Theravance Main Business 11.23.4 Theravance Business Operation 12 COMPANY COMPETITION 12.1 Global Sales by Company 12.1.1 Global Sales by Company 12.1.2 Global Sales Share by Company 12.2 Price & Gross Margin 12.3 Landscape of Major Companies in the Market 12.3.1 Major Companies Product Type List 12.3.1 Manufacturing Regions and Headquarters of Major Companies 12.3.1 Mergers & Acquisitions 12.4 Competitive Environment for New Entrants 12.4.1 Michael Porter's Five Forces Model 12.4.2 SWOT 13 ENVIRONMENT OVERVIEW 13.1 Impact of COVID-19 13.2 Geopolitics Overview 13.3 Economic Overview of Major Countries 14 RESEARCH CONCLUSION

LIST OF TABLE TABLE ~ Opioid-induced Constipation Industry Dynamics & Regulations List TABLE ~ Global Opioid-induced Constipation Sales Volume, Revenue, Price, Cost and Margin, 2016-2021E TABLE ~ Solid Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Solid Market Size (Volume) 2016-2021E and Year-over-year (YOY) Growth (%) 2017-2021E TABLE ~ Liquid Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Liquid Market Size (Volume) 2016-2021E and Year-over-year (YOY) Growth (%) 2017-2021E TABLE ~ Global Opioid-induced Constipation Market Size by Type, 2016-2021E, in USD Million TABLE ~ Global Opioid-induced Constipation Market Size by Type, 2016-2021E, in Volume TABLE ~ Drugstore Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Drugstore Market Size (Volume) 2016-2021E and Year-over-year (YOY) Growth (%) 2017-2021E TABLE ~ Hospital Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Hospital Market Size (Volume) 2016-2021E and Year-over-year (YOY) Growth (%) 2017-2021E TABLE ~ Others Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Others Market Size (Volume) 2016-2021E and Year-over-year (YOY) Growth (%) 2017-2021E TABLE ~ Global Opioid-induced Constipation Market Size by Type, 2016-2021E, in USD Million TABLE ~ Global Opioid-induced Constipation Market Size by Type, 2016-2021E, in Volume TABLE ~ North America Opioid-induced Constipation Sales by Countries 2016-2021E, in USD Million TABLE ~ North America Opioid-induced Constipation Sales Share by Countries 2016-2021E, in USD Million TABLE ~ North America Opioid-induced Constipation Sales by Countries 2016-2021E, in Volume TABLE ~ North America Opioid-induced Constipation Sales Share by Countries 2016-2021E, in Volume TABLE ~ United States Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Canada Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Mexico Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Europe Opioid-induced Constipation Sales by Countries 2016-2021E, in USD Million TABLE ~ Europe Opioid-induced Constipation Sales Share by Countries 2016-2021E, in USD Million TABLE ~ Europe Opioid-induced Constipation Sales by Countries 2016-2021E, in Volume TABLE ~ Europe Opioid-induced Constipation Sales Share by Countries 2016-2021E, in Volume TABLE ~ Germany Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ UK Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ France Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Russia Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Italy Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Rest of Europe Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ ASIA-PACIFIC Opioid-induced Constipation Sales by Countries 2016-2021E, in USD Million TABLE ~ ASIA-PACIFIC Opioid-induced Constipation Sales Share by Countries 2016-2021E, in USD Million TABLE ~ ASIA-PACIFIC Opioid-induced Constipation Sales by Countries 2016-2021E, in Volume TABLE ~ ASIA-PACIFIC Opioid-induced Constipation Sales Share by Countries 2016-2021E, in Volume TABLE ~ China Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ India Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Japan Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ South Korea Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Southeast Asia Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Australia Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Rest of Asia Pacific Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ South America Opioid-induced Constipation Sales by Countries 2016-2021E, in USD Million TABLE ~ South America Opioid-induced Constipation Sales Share by Countries 2016-2021E, in USD Million TABLE ~ South America Opioid-induced Constipation Sales by Countries 2016-2021E, in Volume TABLE ~ South America Opioid-induced Constipation Sales Share by Countries 2016-2021E, in Volume TABLE ~ Brazil Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Argentina Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Rest of South America Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Middle East and Africa Opioid-induced Constipation Sales by Countries 2016-2021E, in USD Million TABLE ~ Middle East and Africa Opioid-induced Constipation Sales Share by Countries 2016-2021E, in USD Million TABLE ~ Middle East and Africa Opioid-induced Constipation Sales by Countries 2016-2021E, in Volume TABLE ~ Middle East and Africa Opioid-induced Constipation Sales Share by Countries 2016-2021E, in Volume TABLE ~ GCC Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ North Africa Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ South Africa Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Rest of Middle East & Africa Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Global Opioid-induced Constipation Sales Forecast by Type 2022F-2026F, in USD Million TABLE ~ Global Opioid-induced Constipation Sales Share Forecast by Type 2022F-2026F, in USD Million TABLE ~ Global Opioid-induced Constipation Sales Forecast by Type 2022F-2026F, in Volume TABLE ~ Global Opioid-induced Constipation Sales Share Forecast by Type 2022F-2026F, in Volume TABLE ~ Global Opioid-induced Constipation Sales Forecast by Application / End-Use 2022F-2026F, in USD Million TABLE ~ Global Opioid-induced Constipation Sales Share Forecast by Application / End-Use 2022F-2026F, in USD Million TABLE ~ Global Opioid-induced Constipation Sales Forecast by Application / End-Use 2022F-2026F, in Volume TABLE ~ Global Opioid-induced Constipation Sales Share Forecast by Application / End-Use 2022F-2026F, in Volume TABLE ~ Global Opioid-induced Constipation Sales Forecast by Region 2022F-2026F, in USD Million TABLE ~ Global Opioid-induced Constipation Sales Share Forecast by Region 2022F-2026F, in USD Million TABLE ~ Global Opioid-induced Constipation Sales Forecast by Region 2022F-2026F, in Volume TABLE ~ Global Opioid-induced Constipation Sales Share Forecast by Region 2022F-2026F, in Volume TABLE ~ AstraZeneca Overview List TABLE ~ Products & Services List of AstraZeneca TABLE ~ Business Operation of AstraZeneca (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ Takeda Pharmaceutical Overview List TABLE ~ Products & Services List of Takeda Pharmaceutical TABLE ~ Business Operation of Takeda Pharmaceutical (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ Valeant Pharmaceuticals International Overview List TABLE ~ Products & Services List of Valeant Pharmaceuticals International TABLE ~ Business Operation of Valeant Pharmaceuticals International (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ Abbott Overview List TABLE ~ Products & Services List of Abbott TABLE ~ Business Operation of Abbott (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ Bayer Overview List TABLE ~ Products & Services List of Bayer TABLE ~ Business Operation of Bayer (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ Boehringer Ingelheim Overview List TABLE ~ Products & Services List of Boehringer Ingelheim TABLE ~ Business Operation of Boehringer Ingelheim (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ C.B. Fleet Overview List TABLE ~ Products & Services List of C.B. Fleet TABLE ~ Business Operation of C.B. Fleet (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ Cosmo Pharmaceuticals Overview List TABLE ~ Products & Services List of Cosmo Pharmaceuticals TABLE ~ Business Operation of Cosmo Pharmaceuticals (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ Daewoong Overview List TABLE ~ Products & Services List of Daewoong TABLE ~ Business Operation of Daewoong (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ Daiichi Sankyo Overview List TABLE ~ Products & Services List of Daiichi Sankyo TABLE ~ Business Operation of Daiichi Sankyo (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ GlaxoSmithKline Overview List TABLE ~ Products & Services List of GlaxoSmithKline TABLE ~ Business Operation of GlaxoSmithKline (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ Ironwood Pharmaceuticals Overview List TABLE ~ Products & Services List of Ironwood Pharmaceuticals TABLE ~ Business Operation of Ironwood Pharmaceuticals (Sales Revenue, Cost, Gross Margin) TABLE ~ Johnson & Johnson Overview List TABLE ~ Products & Services List of Johnson & Johnson TABLE ~ Business Operation of Johnson & Johnson (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ Merck Overview List TABLE ~ Products & Services List of Merck TABLE ~ Business Operation of Merck (Sales Revenue, Cost, Gross Margin) TABLE ~ Mundipharma Overview List TABLE ~ Products & Services List of Mundipharma TABLE ~ Business Operation of Mundipharma (Sales Revenue, Cost, Gross Margin) TABLE ~ Nektar Therapeutics Overview List TABLE ~ Products & Services List of Nektar Therapeutics TABLE ~ Business Operation of Nektar Therapeutics (Sales Revenue, Cost, Gross Margin) TABLE ~ Pfizer Overview List TABLE ~ Products & Services List of Pfizer TABLE ~ Business Operation of Pfizer (Sales Revenue, Cost, Gross Margin) TABLE ~ Progenics Pharmaceuticals Overview List TABLE ~ Products & Services List of Progenics Pharmaceuticals TABLE ~ Business Operation of Progenics Pharmaceuticals (Sales Revenue, Cost, Gross Margin) TABLE ~ Shionogi Overview List TABLE ~ Products & Services List of Shionogi TABLE ~ Business Operation of Shionogi (Sales Revenue, Cost, Gross Margin) TABLE ~ SLA Pharma Overview List TABLE ~ Products & Services List of SLA Pharma TABLE ~ Business Operation of SLA Pharma (Sales Revenue, Cost, Gross Margin) TABLE ~ Sucampo Overview List TABLE ~ Products & Services List of Sucampo TABLE ~ Business Operation of Sucampo (Sales Revenue, Cost, Gross Margin) TABLE ~ Synergy Pharmaceuticals Overview List TABLE ~ Products & Services List of Synergy Pharmaceuticals TABLE ~ Business Operation of Synergy Pharmaceuticals (Sales Revenue, Cost, Gross Margin) TABLE ~ Theravance Overview List TABLE ~ Products & Services List of Theravance TABLE ~ Business Operation of Theravance (Sales Revenue, Cost, Gross Margin) TABLE ~ Global Opioid-induced Constipation Sales by Company 2016-2021E, in USD Million TABLE ~ Global Opioid-induced Constipation Sales by Company 2016-2021E, in Volume TABLE ~ Global Opioid-induced Constipation Sales Share by Company 2016-2021E, in USD Million TABLE ~ Global Opioid-induced Constipation Sales Share by Company 2016-2021E, in Volume TABLE ~ Global Opioid-induced Constipation Sales Price by Company 2016-2021E, in USD/Volume TABLE ~ Global Opioid-induced Constipation Gross Margin by Company 2016-2021E TABLE ~ Major Companies Product Type List TABLE ~ Major Companies Product Type List TABLE ~ Mergers & Acquisitions in the Market