TABLE OF CONTENTS 1 INDUSTRY OVERVIEW 1.1 Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Industry 1.1.1 Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Overview 1.1.2 Terminology Definition in the Report 1.1.2.1 Capacity 1.1.2.2 Sales Volume 1.1.2.3 Sales Revenue 1.1.2.4 Ex-factory Price & Sales Price 1.1.2.5 Cost 1.1.2.6 Gross Margin 1.2 Products & Services Overview Scope 1.3 Dual Specificity Mitogen Activated Protein Kinase Kinase 1 in the Industry Chain 1.4 Industry Dynamics & Regulations 1.5 Global Market Overview 2 UPSTREAM & MANUFACTURING 2.1 Raw Materials / Components 2.2 Procurement Methods & Channels 2.3 Cost Structure & Manufacturing 2.4 Industry Capacity Overview 2.5 Production Distribution by Geography 2.5.1 Production in Major Regions / Countries 2.5.2 Trade Flow Overview 3 PRODUCT SEGMENT 3.1 Product Segmentation Market (2017 to 2021E) 3.1.1 RG-7304 Market 3.1.2 E-6201 Market 3.1.3 Selumetinib Sulfate Market 3.1.4 Others Market 3.2 Market Status 4 APPLICATION / END-USE SEGMENT 4.1 Application Segmentation Market (2016 to 2021E) 4.1.1 Clinic Market 4.1.2 Hospital Market 4.1.3 Others Market 4.2 Market Status 5 NORTH AMERICA 5.1 North America Market Growth 5.2 North America Market by Countries 5.3 Major Countries Market Growth 5.3.1 United States Market Size and Growth (2016-2021E) 5.3.2 Canada Market Size and Growth (2016-2021E) 5.3.3 Mexico Market Size and Growth (2016-2021E) 6 EUROPE 6.1 Europe Market Growth 6.2 Europe Market by Countries 6.3 Major Countries Market Growth 6.3.1 Germany Market Size and Growth (2016-2021E) 6.3.2 UK Market Size and Growth (2016-2021E) 6.3.3 France Market Size and Growth (2016-2021E) 6.3.4 Russia Market Size and Growth (2016-2021E) 6.3.5 Italy Market Size and Growth (2016-2021E) 6.3.6 Rest of Europe Market Size and Growth (2016-2021E) 7 ASIA-PACIFIC 7.1 ASIA-PACIFIC Market Growth 7.2 ASIA-PACIFIC Market by Countries 7.3 Major Countries Market Growth 7.3.1 China Market Size and Growth (2016-2021E) 7.3.2 India Market Size and Growth (2016-2021E) 7.3.3 Japan Market Size and Growth (2016-2021E) 7.3.4 South Korea Market Size and Growth (2016-2021E) 7.3.5 Southeast Asia Market Size and Growth (2016-2021E) 7.3.6 Australia Market Size and Growth (2016-2021E) 7.3.7 Rest of Asia Pacific Market Size and Growth (2016-2021E) 8 SOUTH AMERICA 8.1 South America Market Growth 8.2 South America Market by Countries 8.3 Major Countries Market Growth 8.3.1 Brazil Market Size and Growth (2016-2021E) 8.3.2 Argentina Market Size and Growth (2016-2021E) 8.3.3 Rest of South America Market Size and Growth (2016-2021E) 9 MIDDLE EAST & AFRICA 9.1 Middle East and Africa Market Growth 9.2 Middle East and Africa Market by Countries 9.3 Major Countries Market Growth 9.3.1 GCC Market Size and Growth (2016-2021E) 9.3.2 North Africa Market Size and Growth (2016-2021E) 9.3.3 South Africa Market Size and Growth (2016-2021E) 9.3.4 Rest of Middle East & Africa Market Size and Growth (2016-2021E) 10 MARKET FORECAST 10.1 Global Market Forecast Overview 10.2 Global Market Forecast by Type 10.3 Global Market Forecast by Application / End-Use 10.4 Global Market Forecast by Region 11 COMPETITION OF MAJOR PLAYERS 11.1 Array BioPharma Inc. (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.1.1 Array BioPharma Inc. Profile 11.1.2 Array BioPharma Inc. Products & Services Overview 11.1.3 Array BioPharma Inc. Main Business 11.1.4 Array BioPharma Inc. Business Operation 11.2 AstraZeneca Plc (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.2.1 AstraZeneca Plc Profile 11.2.2 AstraZeneca Plc Products & Services 11.2.3 AstraZeneca Plc Main Business 11.2.4 AstraZeneca Plc Business Operation 11.3 Eisai (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.3.1 Eisai Profile 11.3.2 Eisai Products & Services 11.3.3 Eisai Main Business 11.3.4 Eisai Business Operation 11.4 F. Hoffmann-La Roche Ltd. (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.4.1 F. Hoffmann-La Roche Ltd. Profile 11.4.2 F. Hoffmann-La Roche Ltd. Products & Services 11.4.3 F. Hoffmann-La Roche Ltd. Main Business 11.4.4 F. Hoffmann-La Roche Ltd. Business Operation 11.5 GlaxoSmithKline Plc (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.5.1 GlaxoSmithKline Plc Profile 11.5.2 GlaxoSmithKline Plc Products & Services 11.5.3 GlaxoSmithKline Plc Main Business 11.5.4 GlaxoSmithKline Plc Business Operation 11.6 Merck & Co., Inc. (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.6.1 Merck & Co., Inc. Profile 11.6.2 Merck & Co., Inc. Products & Services 11.6.3 Merck & Co., Inc. Main Business 11.6.4 Merck & Co., Inc. Business Operation 11.7 Merck KGaA (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.7.1 Merck KGaA Profile 11.7.2 Merck KGaA Products & Services 11.7.3 Merck KGaA Main Business 11.7.4 Merck KGaA Business Operation 11.8 Novartis AG (Company Profile, Products Overview, Sales Data, Latest Developments etc.) 11.8.1 Novartis AG Profile 11.8.2 Novartis AG Products & Services 11.8.3 Novartis AG Main Business 11.8.4 Novartis AG Business Operation 12 COMPANY COMPETITION 12.1 Global Sales by Company 12.1.1 Global Sales by Company 12.1.2 Global Sales Share by Company 12.2 Price & Gross Margin 12.3 Landscape of Major Companies in the Market 12.3.1 Major Companies Product Type List 12.3.1 Manufacturing Regions and Headquarters of Major Companies 12.3.1 Mergers & Acquisitions 12.4 Competitive Environment for New Entrants 12.4.1 Michael Porter's Five Forces Model 12.4.2 SWOT 13 ENVIRONMENT OVERVIEW 13.1 Impact of COVID-19 13.2 Geopolitics Overview 13.3 Economic Overview of Major Countries 14 RESEARCH CONCLUSION

LIST OF TABLE TABLE ~ Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Industry Dynamics & Regulations List TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Volume, Revenue, Price, Cost and Margin, 2016-2021E TABLE ~ RG-7304 Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ RG-7304 Market Size (Volume) 2016-2021E and Year-over-year (YOY) Growth (%) 2017-2021E TABLE ~ E-6201 Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ E-6201 Market Size (Volume) 2016-2021E and Year-over-year (YOY) Growth (%) 2017-2021E TABLE ~ Selumetinib Sulfate Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Selumetinib Sulfate Market Size (Volume) 2016-2021E and Year-over-year (YOY) Growth (%) 2017-2021E TABLE ~ Others Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Others Market Size (Volume) 2016-2021E and Year-over-year (YOY) Growth (%) 2017-2021E TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Market Size by Type, 2016-2021E, in USD Million TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Market Size by Type, 2016-2021E, in Volume TABLE ~ Clinic Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Clinic Market Size (Volume) 2016-2021E and Year-over-year (YOY) Growth (%) 2017-2021E TABLE ~ Hospital Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Hospital Market Size (Volume) 2016-2021E and Year-over-year (YOY) Growth (%) 2017-2021E TABLE ~ Others Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Others Market Size (Volume) 2016-2021E and Year-over-year (YOY) Growth (%) 2017-2021E TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Market Size by Type, 2016-2021E, in USD Million TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Market Size by Type, 2016-2021E, in Volume TABLE ~ North America Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales by Countries 2016-2021E, in USD Million TABLE ~ North America Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Share by Countries 2016-2021E, in USD Million TABLE ~ North America Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales by Countries 2016-2021E, in Volume TABLE ~ North America Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Share by Countries 2016-2021E, in Volume TABLE ~ United States Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Canada Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Mexico Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Europe Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales by Countries 2016-2021E, in USD Million TABLE ~ Europe Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Share by Countries 2016-2021E, in USD Million TABLE ~ Europe Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales by Countries 2016-2021E, in Volume TABLE ~ Europe Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Share by Countries 2016-2021E, in Volume TABLE ~ Germany Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ UK Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ France Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Russia Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Italy Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Rest of Europe Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ ASIA-PACIFIC Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales by Countries 2016-2021E, in USD Million TABLE ~ ASIA-PACIFIC Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Share by Countries 2016-2021E, in USD Million TABLE ~ ASIA-PACIFIC Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales by Countries 2016-2021E, in Volume TABLE ~ ASIA-PACIFIC Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Share by Countries 2016-2021E, in Volume TABLE ~ China Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ India Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Japan Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ South Korea Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Southeast Asia Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Australia Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Rest of Asia Pacific Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ South America Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales by Countries 2016-2021E, in USD Million TABLE ~ South America Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Share by Countries 2016-2021E, in USD Million TABLE ~ South America Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales by Countries 2016-2021E, in Volume TABLE ~ South America Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Share by Countries 2016-2021E, in Volume TABLE ~ Brazil Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Argentina Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Rest of South America Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Middle East and Africa Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales by Countries 2016-2021E, in USD Million TABLE ~ Middle East and Africa Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Share by Countries 2016-2021E, in USD Million TABLE ~ Middle East and Africa Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales by Countries 2016-2021E, in Volume TABLE ~ Middle East and Africa Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Share by Countries 2016-2021E, in Volume TABLE ~ GCC Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ North Africa Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ South Africa Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Rest of Middle East & Africa Market Size (USD Million & Volume), Pric (USD/Volume) 2016-2021E TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Forecast by Type 2022F-2026F, in USD Million TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Share Forecast by Type 2022F-2026F, in USD Million TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Forecast by Type 2022F-2026F, in Volume TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Share Forecast by Type 2022F-2026F, in Volume TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Forecast by Application / End-Use 2022F-2026F, in USD Million TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Share Forecast by Application / End-Use 2022F-2026F, in USD Million TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Forecast by Application / End-Use 2022F-2026F, in Volume TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Share Forecast by Application / End-Use 2022F-2026F, in Volume TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Forecast by Region 2022F-2026F, in USD Million TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Share Forecast by Region 2022F-2026F, in USD Million TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Forecast by Region 2022F-2026F, in Volume TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Share Forecast by Region 2022F-2026F, in Volume TABLE ~ Array BioPharma Inc. Overview List TABLE ~ Products & Services List of Array BioPharma Inc. TABLE ~ Business Operation of Array BioPharma Inc. (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ AstraZeneca Plc Overview List TABLE ~ Products & Services List of AstraZeneca Plc TABLE ~ Business Operation of AstraZeneca Plc (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ Eisai Overview List TABLE ~ Products & Services List of Eisai TABLE ~ Business Operation of Eisai (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ F. Hoffmann-La Roche Ltd. Overview List TABLE ~ Products & Services List of F. Hoffmann-La Roche Ltd. TABLE ~ Business Operation of F. Hoffmann-La Roche Ltd. (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ GlaxoSmithKline Plc Overview List TABLE ~ Products & Services List of GlaxoSmithKline Plc TABLE ~ Business Operation of GlaxoSmithKline Plc (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ Merck & Co., Inc. Overview List TABLE ~ Products & Services List of Merck & Co., Inc. TABLE ~ Business Operation of Merck & Co., Inc. (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ Merck KGaA Overview List TABLE ~ Products & Services List of Merck KGaA TABLE ~ Business Operation of Merck KGaA (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ Novartis AG Overview List TABLE ~ Products & Services List of Novartis AG TABLE ~ Business Operation of Novartis AG (Sales Revenue, Sales Volume, Price, Cost, Gross Margin) TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales by Company 2016-2021E, in USD Million TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales by Company 2016-2021E, in Volume TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Share by Company 2016-2021E, in USD Million TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Share by Company 2016-2021E, in Volume TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Sales Price by Company 2016-2021E, in USD/Volume TABLE ~ Global Dual Specificity Mitogen Activated Protein Kinase Kinase 1 Gross Margin by Company 2016-2021E TABLE ~ Major Companies Product Type List TABLE ~ Major Companies Product Type List TABLE ~ Mergers & Acquisitions in the Market