1 Report Overview 1.1 Study Scope 1.2 Market Analysis by Type 1.2.1 Global Ubiquitin Proteasome Market Size Growth Rate by Type: 2016 VS 2021 VS 2027 1.2.2 Velcade 1.2.3 Kyprolis 1.3 Market by Application 1.3.1 Global Ubiquitin Proteasome Market Share by Application: 2016 VS 2021 VS 2027 1.3.2 Cancers 1.3.3 Neurodegenerative Disorders 1.3.4 Others 1.4 Study Objectives 1.5 Years Considered 2 Global Growth Trends 2.1 Global Ubiquitin Proteasome Market Perspective (2016-2027) 2.2 Ubiquitin Proteasome Growth Trends by Regions 2.2.1 Ubiquitin Proteasome Market Size by Regions: 2016 VS 2021 VS 2027 2.2.2 Ubiquitin Proteasome Historic Market Share by Regions (2016-2021) 2.2.3 Ubiquitin Proteasome Forecasted Market Size by Regions (2022-2027) 2.3 Ubiquitin Proteasome Industry Dynamic 2.3.1 Ubiquitin Proteasome Market Trends 2.3.2 Ubiquitin Proteasome Market Drivers 2.3.3 Ubiquitin Proteasome Market Challenges 2.3.4 Ubiquitin Proteasome Market Restraints 3 Competition Landscape by Key Players 3.1 Global Top Ubiquitin Proteasome Players by Revenue 3.1.1 Global Top Ubiquitin Proteasome Players by Revenue (2016-2021) 3.1.2 Global Ubiquitin Proteasome Revenue Market Share by Players (2016-2021) 3.2 Global Ubiquitin Proteasome Market Share by Company Type (Tier 1, Tier 2 and Tier 3) 3.3 Players Covered: Ranking by Ubiquitin Proteasome Revenue 3.4 Global Ubiquitin Proteasome Market Concentration Ratio 3.4.1 Global Ubiquitin Proteasome Market Concentration Ratio (CR5 and HHI) 3.4.2 Global Top 10 and Top 5 Companies by Ubiquitin Proteasome Revenue in 2020 3.5 Ubiquitin Proteasome Key Players Head office and Area Served 3.6 Key Players Ubiquitin Proteasome Product Solution and Service 3.7 Date of Enter into Ubiquitin Proteasome Market 3.8 Mergers & Acquisitions, Expansion Plans 4 Ubiquitin Proteasome Breakdown Data by Type 4.1 Global Ubiquitin Proteasome Historic Market Size by Type (2016-2021) 4.2 Global Ubiquitin Proteasome Forecasted Market Size by Type (2022-2027) 5 Ubiquitin Proteasome Breakdown Data by Application 5.1 Global Ubiquitin Proteasome Historic Market Size by Application (2016-2021) 5.2 Global Ubiquitin Proteasome Forecasted Market Size by Application (2022-2027) 6 North America 6.1 North America Ubiquitin Proteasome Market Size (2016-2027) 6.2 North America Ubiquitin Proteasome Market Size by Type 6.2.1 North America Ubiquitin Proteasome Market Size by Type (2016-2021) 6.2.2 North America Ubiquitin Proteasome Market Size by Type (2022-2027) 6.2.3 North America Ubiquitin Proteasome Market Size by Type (2016-2027) 6.3 North America Ubiquitin Proteasome Market Size by Application 6.3.1 North America Ubiquitin Proteasome Market Size by Application (2016-2021) 6.3.2 North America Ubiquitin Proteasome Market Size by Application (2022-2027) 6.3.3 North America Ubiquitin Proteasome Market Size by Application (2016-2027) 6.4 North America Ubiquitin Proteasome Market Size by Country 6.4.1 North America Ubiquitin Proteasome Market Size by Country (2016-2021) 6.4.2 North America Ubiquitin Proteasome Market Size by Country (2022-2027) 6.4.3 United States 6.4.4 Canada 7 Europe 7.1 Europe Ubiquitin Proteasome Market Size (2016-2027) 7.2 Europe Ubiquitin Proteasome Market Size by Type 7.2.1 Europe Ubiquitin Proteasome Market Size by Type (2016-2021) 7.2.2 Europe Ubiquitin Proteasome Market Size by Type (2022-2027) 7.2.3 Europe Ubiquitin Proteasome Market Size by Type (2016-2027) 7.3 Europe Ubiquitin Proteasome Market Size by Application 7.3.1 Europe Ubiquitin Proteasome Market Size by Application (2016-2021) 7.3.2 Europe Ubiquitin Proteasome Market Size by Application (2022-2027) 7.3.3 Europe Ubiquitin Proteasome Market Size by Application (2016-2027) 7.4 Europe Ubiquitin Proteasome Market Size by Country 7.4.1 Europe Ubiquitin Proteasome Market Size by Country (2016-2021) 7.4.2 Europe Ubiquitin Proteasome Market Size by Country (2022-2027) 7.4.3 Germany 7.4.4 France 7.4.5 U.K. 7.4.6 Italy 7.4.7 Russia 7.4.8 Nordic 8 Asia-Pacific 8.1 Asia-Pacific Ubiquitin Proteasome Market Size (2016-2027) 8.2 Asia-Pacific Ubiquitin Proteasome Market Size by Type 8.2.1 Asia-Pacific Ubiquitin Proteasome Market Size by Type (2016-2021) 8.2.2 Asia-Pacific Ubiquitin Proteasome Market Size by Type (2022-2027) 8.2.3 Asia-Pacific Ubiquitin Proteasome Market Size by Type (2016-2027) 8.3 Asia-Pacific Ubiquitin Proteasome Market Size by Application 8.3.1 Asia-Pacific Ubiquitin Proteasome Market Size by Application (2016-2021) 8.3.2 Asia-Pacific Ubiquitin Proteasome Market Size by Application (2022-2027) 8.3.3 Asia-Pacific Ubiquitin Proteasome Market Size by Application (2016-2027) 8.4 Asia-Pacific Ubiquitin Proteasome Market Size by Region 8.4.1 Asia-Pacific Ubiquitin Proteasome Market Size by Region (2016-2021) 8.4.2 Asia-Pacific Ubiquitin Proteasome Market Size by Region (2022-2027) 8.4.3 China 8.4.4 Japan 8.4.5 South Korea 8.4.6 Southeast Asia 8.4.7 India 8.4.8 Australia 9 Latin America 9.1 Latin America Ubiquitin Proteasome Market Size (2016-2027) 9.2 Latin America Ubiquitin Proteasome Market Size by Type 9.2.1 Latin America Ubiquitin Proteasome Market Size by Type (2016-2021) 9.2.2 Latin America Ubiquitin Proteasome Market Size by Type (2022-2027) 9.2.3 Latin America Ubiquitin Proteasome Market Size by Type (2016-2027) 9.3 Latin America Ubiquitin Proteasome Market Size by Application 9.3.1 Latin America Ubiquitin Proteasome Market Size by Application (2016-2021) 9.3.2 Latin America Ubiquitin Proteasome Market Size by Application (2022-2027) 9.3.3 Latin America Ubiquitin Proteasome Market Size by Application (2016-2027) 9.4 Latin America Ubiquitin Proteasome Market Size by Country 9.4.1 Latin America Ubiquitin Proteasome Market Size by Country (2016-2021) 9.4.2 Latin America Ubiquitin Proteasome Market Size by Country (2022-2027) 9.4.3 Mexico 9.4.4 Brazil 10 Middle East & Africa 10.1 Middle East & Africa Ubiquitin Proteasome Market Size (2016-2027) 10.2 Middle East & Africa Ubiquitin Proteasome Market Size by Type 10.2.1 Middle East & Africa Ubiquitin Proteasome Market Size by Type (2016-2021) 10.2.2 Middle East & Africa Ubiquitin Proteasome Market Size by Type (2022-2027) 10.2.3 Middle East & Africa Ubiquitin Proteasome Market Size by Type (2016-2027) 10.3 Middle East & Africa Ubiquitin Proteasome Market Size by Application 10.3.1 Middle East & Africa Ubiquitin Proteasome Market Size by Application (2016-2021) 10.3.2 Middle East & Africa Ubiquitin Proteasome Market Size by Application (2022-2027) 10.3.3 Middle East & Africa Ubiquitin Proteasome Market Size by Application (2016-2027) 10.4 Middle East & Africa Ubiquitin Proteasome Market Size by Country 10.4.1 Middle East & Africa Ubiquitin Proteasome Market Size by Country (2016-2021) 10.4.2 Middle East & Africa Ubiquitin Proteasome Market Size by Country (2022-2027) 10.4.3 Turkey 10.4.4 Saudi Arabia 10.4.5 UAE 11 Key Players Profiles 11.1 Johnson & Johnson 11.1.1 Johnson & Johnson Company Details 11.1.2 Johnson & Johnson Business Overview 11.1.3 Johnson & Johnson Ubiquitin Proteasome Introduction 11.1.4 Johnson & Johnson Revenue in Ubiquitin Proteasome Business (2016-2021) 11.1.5 Johnson & Johnson Recent Development 11.2 F.Hoffmann-La Roche 11.2.1 F.Hoffmann-La Roche Company Details 11.2.2 F.Hoffmann-La Roche Business Overview 11.2.3 F.Hoffmann-La Roche Ubiquitin Proteasome Introduction 11.2.4 F.Hoffmann-La Roche Revenue in Ubiquitin Proteasome Business (2016-2021) 11.2.5 F.Hoffmann-La Roche Recent Development 11.3 Novelix Pharmaceuticals 11.3.1 Novelix Pharmaceuticals Company Details 11.3.2 Novelix Pharmaceuticals Business Overview 11.3.3 Novelix Pharmaceuticals Ubiquitin Proteasome Introduction 11.3.4 Novelix Pharmaceuticals Revenue in Ubiquitin Proteasome Business (2016-2021) 11.3.5 Novelix Pharmaceuticals Recent Development 11.4 GlaxoSmithKline 11.4.1 GlaxoSmithKline Company Details 11.4.2 GlaxoSmithKline Business Overview 11.4.3 GlaxoSmithKline Ubiquitin Proteasome Introduction 11.4.4 GlaxoSmithKline Revenue in Ubiquitin Proteasome Business (2016-2021) 11.4.5 GlaxoSmithKline Recent Development 11.5 Onyx Pharmaceuticals 11.5.1 Onyx Pharmaceuticals Company Details 11.5.2 Onyx Pharmaceuticals Business Overview 11.5.3 Onyx Pharmaceuticals Ubiquitin Proteasome Introduction 11.5.4 Onyx Pharmaceuticals Revenue in Ubiquitin Proteasome Business (2016-2021) 11.5.5 Onyx Pharmaceuticals Recent Development 12 Analyst's Viewpoints/Conclusions 13 Appendix 13.1 Research Methodology 13.1.1 Methodology/Research Approach 13.1.2 Data Source 13.2 Disclaimer 13.3 Author Details

List of Tables Table 1. Global Ubiquitin Proteasome Market Size Growth Rate by Type (US$ Million):2016 VS 2021 VS 2027 Table 2. Key Players of Velcade Table 3. Key Players of Kyprolis Table 4. Global Ubiquitin Proteasome Market Size Growth by Application (US$ Million): 2016 VS 2021 VS 2027 Table 5. Global Ubiquitin Proteasome Market Size by Regions (US$ Million): 2016 VS 2021 VS 2027 Table 6. Global Ubiquitin Proteasome Market Size by Regions (2016-2021) & (US$ Million) Table 7. Global Ubiquitin Proteasome Market Share by Regions (2016-2021) Table 8. Global Ubiquitin Proteasome Forecasted Market Size by Regions (2022-2027) & (US$ Million) Table 9. Global Ubiquitin Proteasome Market Share by Regions (2022-2027) Table 10. Ubiquitin Proteasome Market Trends Table 11. Ubiquitin Proteasome Market Drivers Table 12. Ubiquitin Proteasome Market Challenges Table 13. Ubiquitin Proteasome Market Restraints Table 14. Global Ubiquitin Proteasome Revenue by Players (2016-2021) & (US$ Million) Table 15. Global Ubiquitin Proteasome Market Share by Players (2016-2021) Table 16. Global Top Ubiquitin Proteasome Players by Company Type (Tier 1, Tier 2 and Tier 3) (based on the Revenue in Ubiquitin Proteasome as of 2020) Table 17. Ranking of Global Top Ubiquitin Proteasome Companies by Revenue (US$ Million) in 2020 Table 18. Global 5 Largest Players Market Share by Ubiquitin Proteasome Revenue (CR5 and HHI) & (2016-2021) Table 19. Key Players Headquarters and Area Served Table 20. Key Players Ubiquitin Proteasome Product Solution and Service Table 21. Date of Enter into Ubiquitin Proteasome Market Table 22. Mergers & Acquisitions, Expansion Plans Table 23. Global Ubiquitin Proteasome Market Size by Type (2016-2021) (US$ Million) Table 24. Global Ubiquitin Proteasome Revenue Market Share by Type (2016-2021) Table 25. Global Ubiquitin Proteasome Forecasted Market Size by Type (2022-2027) (US$ Million) Table 26. Global Ubiquitin Proteasome Revenue Market Share by Type (2022-2027) & (US$ Million) Table 27. Global Ubiquitin Proteasome Market Size Share by Application (2016-2021) & (US$ Million) Table 28. Global Ubiquitin Proteasome Revenue Market Share by Application (2016-2021) Table 29. Global Ubiquitin Proteasome Forecasted Market Size by Application (2022-2027) (US$ Million) Table 30. Global Ubiquitin Proteasome Revenue Market Share by Application (2022-2027) & (US$ Million) Table 31. North America Ubiquitin Proteasome Market Size by Type (2016-2021) (US$ Million) Table 32. North America Ubiquitin Proteasome Market Size by Type (2022-2027) & (US$ Million) Table 33. North America Ubiquitin Proteasome Market Size by Application (2016-2021) (US$ Million) Table 34. North America Ubiquitin Proteasome Market Size by Application (2022-2027) & (US$ Million) Table 35. North America Ubiquitin Proteasome Market Size by Country (2016-2021) & (US$ Million) Table 36. North America Ubiquitin Proteasome Market Size by Country (2022-2027) & (US$ Million) Table 37. Europe Ubiquitin Proteasome Market Size by Type (2016-2021) (US$ Million) Table 38. Europe Ubiquitin Proteasome Market Size by Type (2022-2027) & (US$ Million) Table 39. Europe Ubiquitin Proteasome Market Size by Application (2016-2021) (US$ Million) Table 40. Europe Ubiquitin Proteasome Market Size by Application (2022-2027) & (US$ Million) Table 41. Europe Ubiquitin Proteasome Market Size by Country (2016-2021) & (US$ Million) Table 42. Europe Ubiquitin Proteasome Market Size by Country (2022-2027) & (US$ Million) Table 43. Asia-Pacific Ubiquitin Proteasome Market Size by Type (2016-2021) (US$ Million) Table 44. Asia-Pacific Ubiquitin Proteasome Market Size by Type (2022-2027) & (US$ Million) Table 45. Asia-Pacific Ubiquitin Proteasome Market Size by Application (2016-2021) (US$ Million) Table 46. Asia-Pacific Ubiquitin Proteasome Market Size by Application (2022-2027) & (US$ Million) Table 47. Asia-Pacific Ubiquitin Proteasome Market Size by Region (2016-2021) & (US$ Million) Table 48. Asia-Pacific Ubiquitin Proteasome Market Size by Region (2022-2027) & (US$ Million) Table 49. Latin America Ubiquitin Proteasome Market Size by Type (2016-2021) (US$ Million) Table 50. Latin America Ubiquitin Proteasome Market Size by Type (2022-2027) & (US$ Million) Table 51. Latin America Ubiquitin Proteasome Market Size by Application (2016-2021) (US$ Million) Table 52. Latin America Ubiquitin Proteasome Market Size by Application (2022-2027) & (US$ Million) Table 53. Latin America Ubiquitin Proteasome Market Size by Country (2016-2021) & (US$ Million) Table 54. Latin America Ubiquitin Proteasome Market Size by Country (2022-2027) & (US$ Million) Table 55. Middle East & Africa Ubiquitin Proteasome Market Size by Type (2016-2021) (US$ Million) Table 56. Middle East & Africa Ubiquitin Proteasome Market Size by Type (2022-2027) & (US$ Million) Table 57. Middle East & Africa Ubiquitin Proteasome Market Size by Application (2016-2021) (US$ Million) Table 58. Middle East & Africa Ubiquitin Proteasome Market Size by Application (2022-2027) & (US$ Million) Table 59. Middle East & Africa Ubiquitin Proteasome Market Size by Country (2016-2021) & (US$ Million) Table 60. Middle East & Africa Ubiquitin Proteasome Market Size by Country (2022-2027) & (US$ Million) Table 61. Johnson & Johnson Company Details Table 62. Johnson & Johnson Business Overview Table 63. Johnson & Johnson Ubiquitin Proteasome Product Table 64. Johnson & Johnson Revenue in Ubiquitin Proteasome Business (2016-2021) & (US$ Million) Table 65. Johnson & Johnson Recent Development Table 66. F.Hoffmann-La Roche Company Details Table 67. F.Hoffmann-La Roche Business Overview Table 68. F.Hoffmann-La Roche Ubiquitin Proteasome Product Table 69. F.Hoffmann-La Roche Revenue in Ubiquitin Proteasome Business (2016-2021) & (US$ Million) Table 70. F.Hoffmann-La Roche Recent Development Table 71. Novelix Pharmaceuticals Company Details Table 72. Novelix Pharmaceuticals Business Overview Table 73. Novelix Pharmaceuticals Ubiquitin Proteasome Product Table 74. Novelix Pharmaceuticals Revenue in Ubiquitin Proteasome Business (2016-2021) & (US$ Million) Table 75. Novelix Pharmaceuticals Recent Development Table 76. GlaxoSmithKline Company Details Table 77. GlaxoSmithKline Business Overview Table 78. GlaxoSmithKline Ubiquitin Proteasome Product Table 79. GlaxoSmithKline Revenue in Ubiquitin Proteasome Business (2016-2021) & (US$ Million) Table 80. GlaxoSmithKline Recent Development Table 81. Onyx Pharmaceuticals Company Details Table 82. Onyx Pharmaceuticals Business Overview Table 83. Onyx Pharmaceuticals Ubiquitin Proteasome Product Table 84. Onyx Pharmaceuticals Revenue in Ubiquitin Proteasome Business (2016-2021) & (US$ Million) Table 85. Onyx Pharmaceuticals Recent Development Table 86. Research Programs/Design for This Report Table 87. Key Data Information from Secondary Sources Table 88. Key Data Information from Primary Sources List of Figures Figure 1. Global Ubiquitin Proteasome Market Share by Type: 2020 VS 2027 Figure 2. Velcade Features Figure 3. Kyprolis Features Figure 4. Global Ubiquitin Proteasome Market Share by Application: 2020 VS 2027 Figure 5. Cancers Case Studies Figure 6. Neurodegenerative Disorders Case Studies Figure 7. Others Case Studies Figure 8. Ubiquitin Proteasome Report Years Considered Figure 9. Global Ubiquitin Proteasome Market Size (US$ Million), Year-over-Year: 2016-2027 Figure 10. Global Ubiquitin Proteasome Market Size (US$ Million), 2016 VS 2021 VS 2027 Figure 11. Global Ubiquitin Proteasome Market Share by Regions: 2020 VS 2027 Figure 12. Global Ubiquitin Proteasome Market Share by Regions (2022-2027) Figure 13. Global Ubiquitin Proteasome Market Share by Players in 2020 Figure 14. Global Top Ubiquitin Proteasome Players by Company Type (Tier 1, Tier 2 and Tier 3) (based on the Revenue in Ubiquitin Proteasome as of 2020 Figure 15. The Top 10 and 5 Players Market Share by Ubiquitin Proteasome Revenue in 2020 Figure 16. Global Ubiquitin Proteasome Revenue Market Share by Type (2016-2021) Figure 17. Global Ubiquitin Proteasome Revenue Market Share by Type (2022-2027) Figure 18. North America Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 19. North America Ubiquitin Proteasome Market Share by Type (2016-2027) Figure 20. North America Ubiquitin Proteasome Market Share by Application (2016-2027) Figure 21. North America Ubiquitin Proteasome Market Share by Country (2016-2027) Figure 22. United States Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 23. Canada Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 24. Europe Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 25. Europe Ubiquitin Proteasome Market Share by Type (2016-2027) Figure 26. Europe Ubiquitin Proteasome Market Share by Application (2016-2027) Figure 27. Europe Ubiquitin Proteasome Market Share by Country (2016-2027) Figure 28. Germany Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 29. France Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 30. U.K. Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 31. Italy Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 32. Russia Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 33. Nordic Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 34. Asia-Pacific Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 35. Asia-Pacific Ubiquitin Proteasome Market Share by Type (2016-2027) Figure 36. Asia-Pacific Ubiquitin Proteasome Market Share by Application (2016-2027) Figure 37. Asia-Pacific Ubiquitin Proteasome Market Share by Region (2016-2027) Figure 38. China Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 39. Japan Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 40. South Korea Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 41. Southeast Asia Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 42. India Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 43. Australia Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 44. Latin America Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 45. Latin America Ubiquitin Proteasome Market Share by Type (2016-2027) Figure 46. Latin America Ubiquitin Proteasome Market Share by Application (2016-2027) Figure 47. Latin America Ubiquitin Proteasome Market Share by Country (2016-2027) Figure 48. Mexico Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 49. Brazil Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 50. Middle East & Africa Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 51. Middle East & Africa Ubiquitin Proteasome Market Share by Type (2016-2027) Figure 52. Middle East & Africa Ubiquitin Proteasome Market Share by Application (2016-2027) Figure 53. Middle East & Africa Ubiquitin Proteasome Market Share by Country (2016-2027) Figure 54. Turkey Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 55. Saudi Arabia Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 56. UAE Ubiquitin Proteasome Market Size YoY Growth (2016-2027) & (US$ Million) Figure 57. Johnson & Johnson Revenue Growth Rate in Ubiquitin Proteasome Business (2016-2021) Figure 58. F.Hoffmann-La Roche Revenue Growth Rate in Ubiquitin Proteasome Business (2016-2021) Figure 59. Novelix Pharmaceuticals Revenue Growth Rate in Ubiquitin Proteasome Business (2016-2021) Figure 60. GlaxoSmithKline Revenue Growth Rate in Ubiquitin Proteasome Business (2016-2021) Figure 61. Onyx Pharmaceuticals Revenue Growth Rate in Ubiquitin Proteasome Business (2016-2021) Figure 62. Bottom-up and Top-down Approaches for This Report Figure 63. Data Triangulation Figure 64. Key Executives Interviewed

Johnson & Johnson F.Hoffmann-La Roche Novelix Pharmaceuticals GlaxoSmithKline Onyx Pharmaceuticals