1 Tracleer (bosentan) Market Overview 1.1 Product Overview and Scope of Tracleer (bosentan) 1.2 Tracleer (bosentan) Segment by Type 1.2.1 Global Tracleer (bosentan) Sales Growth Rate Comparison by Type (2021-2027) 1.2.2 62.5 mg Tablet 1.2.3 125 mg Tablet 1.3 Tracleer (bosentan) Segment by Application 1.3.1 Global Tracleer (bosentan) Sales Comparison by Application: (2021-2027) 1.3.2 Pediatric Patients 1.3.3 Adult Patients 1.4 Global Tracleer (bosentan) Market Size Estimates and Forecasts 1.4.1 Global Tracleer (bosentan) Revenue 2016-2027 1.4.2 Global Tracleer (bosentan) Sales 2016-2027 1.4.3 Tracleer (bosentan) Market Size by Region: 2016 Versus 2021 Versus 2027 2 Tracleer (bosentan) Market Competition by Manufacturers 2.1 Global Tracleer (bosentan) Sales Market Share by Manufacturers (2016-2021) 2.2 Global Tracleer (bosentan) Revenue Market Share by Manufacturers (2016-2021) 2.3 Global Tracleer (bosentan) Average Price by Manufacturers (2016-2021) 2.4 Manufacturers Tracleer (bosentan) Manufacturing Sites, Area Served, Product Type 2.5 Tracleer (bosentan) Market Competitive Situation and Trends 2.5.1 Tracleer (bosentan) Market Concentration Rate 2.5.2 The Global Top 5 and Top 10 Largest Tracleer (bosentan) Players Market Share by Revenue 2.5.3 Global Tracleer (bosentan) Market Share by Company Type (Tier 1, Tier 2 and Tier 3) 2.6 Manufacturers Mergers & Acquisitions, Expansion Plans 3 Tracleer (bosentan) Retrospective Market Scenario by Region 3.1 Global Tracleer (bosentan) Retrospective Market Scenario in Sales by Region: 2016-2021 3.2 Global Tracleer (bosentan) Retrospective Market Scenario in Revenue by Region: 2016-2021 3.3 North America Tracleer (bosentan) Market Facts & Figures by Country 3.3.1 North America Tracleer (bosentan) Sales by Country 3.3.2 North America Tracleer (bosentan) Revenue by Country 3.3.3 U.S. 3.3.4 Canada 3.4 Europe Tracleer (bosentan) Market Facts & Figures by Country 3.4.1 Europe Tracleer (bosentan) Sales by Country 3.4.2 Europe Tracleer (bosentan) Revenue by Country 3.4.3 Germany 3.4.4 France 3.4.5 U.K. 3.4.6 Italy 3.4.7 Russia 3.5 Asia Pacific Tracleer (bosentan) Market Facts & Figures by Region 3.5.1 Asia Pacific Tracleer (bosentan) Sales by Region 3.5.2 Asia Pacific Tracleer (bosentan) Revenue by Region 3.5.3 China 3.5.4 Japan 3.5.5 South Korea 3.5.6 India 3.5.7 Australia 3.5.8 Taiwan 3.5.9 Indonesia 3.5.10 Thailand 3.5.11 Malaysia 3.5.12 Philippines 3.5.13 Vietnam 3.6 Latin America Tracleer (bosentan) Market Facts & Figures by Country 3.6.1 Latin America Tracleer (bosentan) Sales by Country 3.6.2 Latin America Tracleer (bosentan) Revenue by Country 3.6.3 Mexico 3.6.4 Brazil 3.6.5 Argentina 3.7 Middle East and Africa Tracleer (bosentan) Market Facts & Figures by Country 3.7.1 Middle East and Africa Tracleer (bosentan) Sales by Country 3.7.2 Middle East and Africa Tracleer (bosentan) Revenue by Country 3.7.3 Turkey 3.7.4 Saudi Arabia 3.7.5 U.A.E 4 Global Tracleer (bosentan) Historic Market Analysis by Type 4.1 Global Tracleer (bosentan) Sales Market Share by Type (2016-2021) 4.2 Global Tracleer (bosentan) Revenue Market Share by Type (2016-2021) 4.3 Global Tracleer (bosentan) Price by Type (2016-2021) 5 Global Tracleer (bosentan) Historic Market Analysis by Application 5.1 Global Tracleer (bosentan) Sales Market Share by Application (2016-2021) 5.2 Global Tracleer (bosentan) Revenue Market Share by Application (2016-2021) 5.3 Global Tracleer (bosentan) Price by Application (2016-2021) 6 Key Companies Profiled 6.1 Actelion Pharmaceuticals 6.1.1 Actelion Pharmaceuticals Corporation Information 6.1.2 Actelion Pharmaceuticals Description and Business Overview 6.1.3 Actelion Pharmaceuticals Tracleer (bosentan) Sales, Revenue and Gross Margin (2016-2021) 6.1.4 Actelion Pharmaceuticals Tracleer (bosentan) Product Portfolio 6.1.5 Actelion Pharmaceuticals Recent Developments/Updates 7 Tracleer (bosentan) Manufacturing Cost Analysis 7.1 Tracleer (bosentan) Key Raw Materials Analysis 7.1.1 Key Raw Materials 7.1.2 Key Suppliers of Raw Materials 7.2 Proportion of Manufacturing Cost Structure 7.3 Manufacturing Process Analysis of Tracleer (bosentan) 7.4 Tracleer (bosentan) Industrial Chain Analysis 8 Marketing Channel, Distributors and Customers 8.1 Marketing Channel 8.2 Tracleer (bosentan) Distributors List 8.3 Tracleer (bosentan) Customers 9 Tracleer (bosentan) Market Dynamics 9.1 Tracleer (bosentan) Industry Trends 9.2 Tracleer (bosentan) Growth Drivers 9.3 Tracleer (bosentan) Market Challenges 9.4 Tracleer (bosentan) Market Restraints 10 Global Market Forecast 10.1 Tracleer (bosentan) Market Estimates and Projections by Type 10.1.1 Global Forecasted Sales of Tracleer (bosentan) by Type (2022-2027) 10.1.2 Global Forecasted Revenue of Tracleer (bosentan) by Type (2022-2027) 10.2 Tracleer (bosentan) Market Estimates and Projections by Application 10.2.1 Global Forecasted Sales of Tracleer (bosentan) by Application (2022-2027) 10.2.2 Global Forecasted Revenue of Tracleer (bosentan) by Application (2022-2027) 10.3 Tracleer (bosentan) Market Estimates and Projections by Region 10.3.1 Global Forecasted Sales of Tracleer (bosentan) by Region (2022-2027) 10.3.2 Global Forecasted Revenue of Tracleer (bosentan) by Region (2022-2027) 11 Research Finding and Conclusion 12 Methodology and Data Source 12.1 Methodology/Research Approach 12.1.1 Research Programs/Design 12.1.2 Market Size Estimation 12.1.3 Market Breakdown and Data Triangulation 12.2 Data Source 12.2.1 Secondary Sources 12.2.2 Primary Sources 12.3 Author List 12.4 Disclaimer

List of Tables Table 1. Global Tracleer (bosentan) Sales (K Units) Growth Rate Comparison by Type (2021-2027) Table 2. Global Tracleer (bosentan) Sales (K Units) Comparison by Application (2021-2027) Table 3. Global Tracleer (bosentan) Market Size by Region (US$ Million) (2016 VS 2021 VS 2027) Table 4. Key Manufacturers Tracleer (bosentan) Covered in This Study Table 5. Global Tracleer (bosentan) Sales (K Units) of Key Manufacturers (2016-2021) Table 6. Global Tracleer (bosentan) Sales Market Share by Manufacturers (2016-2021) Table 7. Global Tracleer (bosentan) Revenue (US$ Million) by Manufacturers (2016-2021) Table 8. Global Tracleer (bosentan) Revenue Share by Manufacturers (2016-2021) Table 9. Global Market Tracleer (bosentan) Average Price (USD/Unit) of Key Manufacturers (2016-2021) Table 10. Manufacturers Tracleer (bosentan) Manufacturing Sites and Area Served Table 11. Manufacturers Tracleer (bosentan) Product Type Table 12. Global Manufacturers Market Concentration Ratio (CR5 and HHI) Table 13. Global Tracleer (bosentan) by Company Type (Tier 1, Tier 2 and Tier 3) (based on the Revenue in Tracleer (bosentan) as of 2020) Table 14. Manufacturers Mergers & Acquisitions, Expansion Plans Table 15. Global Tracleer (bosentan) Sales by Region (2016-2021) & (K Units) Table 16. Global Tracleer (bosentan) Sales Market Share by Region (2016-2021) Table 17. Global Tracleer (bosentan) Revenue by Region (2016-2021) & (US$ Million) Table 18. North America Tracleer (bosentan) Sales by Country (2016-2021) & (K Units) Table 19. North America Tracleer (bosentan) Sales Market Share by Country (2016-2021) Table 20. North America Tracleer (bosentan) Revenue by Country (2016-2021) & (US$ Million) Table 21. North America Tracleer (bosentan) Revenue Market Share by Country (2016-2021) Table 22. Europe Tracleer (bosentan) Sales by Country (2016-2021) & (K Units) Table 23. Europe Tracleer (bosentan) Sales Market Share by Country (2016-2021) Table 24. Europe Tracleer (bosentan) Revenue by Country (2016-2021) & (US$ Million) Table 25. Europe Tracleer (bosentan) Revenue Market Share by Country (2016-2021) Table 26. Asia Pacific Tracleer (bosentan) Sales by Region (2016-2021) & (K Units) Table 27. Asia Pacific Tracleer (bosentan) Sales Market Share by Region (2016-2021) Table 28. Asia Pacific Tracleer (bosentan) Revenue by Region (2016-2021) & (US$ Million) Table 29. Asia Pacific Tracleer (bosentan) Revenue Market Share by Region (2016-2021) Table 30. Latin America Tracleer (bosentan) Sales by Country (2016-2021) & (K Units) Table 31. Latin America Tracleer (bosentan) Sales Market Share by Country (2016-2021) Table 32. Latin America Tracleer (bosentan) Revenue by Country (2016-2021) & (US$ Million) Table 33. Latin America Tracleer (bosentan) Revenue Market Share by Country (2016-2021) Table 34. Middle East and Africa Tracleer (bosentan) Sales by Country (2016-2021) & (K Units) Table 35. Middle East and Africa Tracleer (bosentan) Sales Market Share by Country (2016-2021) Table 36. Middle East and Africa Tracleer (bosentan) Revenue by Country (2016-2021) & (US$ Million) Table 37. Middle East and Africa Tracleer (bosentan) Revenue Market Share by Country (2016-2021) Table 38. Global Tracleer (bosentan) Sales (K Units) by Type (2016-2021) Table 39. Global Tracleer (bosentan) Sales Market Share by Type (2016-2021) Table 40. Global Tracleer (bosentan) Revenue (Million US$) by Type (2016-2021) Table 41. Global Tracleer (bosentan) Revenue Share by Type (2016-2021) Table 42. Global Tracleer (bosentan) Price (USD/Unit) by Type (2016-2021) Table 43. Global Tracleer (bosentan) Sales (K Units) by Application (2016-2021) Table 44. Global Tracleer (bosentan) Sales Market Share by Application (2016-2021) Table 45. Global Tracleer (bosentan) Revenue (Million US$) by Application (2016-2021) Table 46. Global Tracleer (bosentan) Revenue Share by Application (2016-2021) Table 47. Global Tracleer (bosentan) Price (USD/Unit) by Application (2016-2021) Table 48. Actelion Pharmaceuticals Corporation Information Table 49. Actelion Pharmaceuticals Description and Business Overview Table 50. Actelion Pharmaceuticals Tracleer (bosentan) Sales (K Units), Revenue (Million US$), Price (USD/Unit) and Gross Margin (2016-2021) Table 51. Actelion Pharmaceuticals Tracleer (bosentan) Product Table 52. Actelion Pharmaceuticals Recent Developments/Updates Table 53. Production Base and Market Concentration Rate of Raw Material Table 54. Key Suppliers of Raw Materials Table 55. Tracleer (bosentan) Distributors List Table 56. Tracleer (bosentan) Customers List Table 57. Tracleer (bosentan) Market Trends Table 58. Tracleer (bosentan) Growth Drivers Table 59. Tracleer (bosentan) Market Challenges Table 60. Tracleer (bosentan) Market Restraints Table 61. Global Tracleer (bosentan) Sales Forecast by Type (2022-2027) & (K Units) Table 62. Global Tracleer (bosentan) Sales Market Share Forecast by Type (2022-2027) Table 63. Global Tracleer (bosentan) Revenue Forecast by Type (2022-2027) & (US$ Million) Table 64. Global Tracleer (bosentan) Revenue Market Share Forecast by Type (2022-2027) Table 65. Global Tracleer (bosentan) Sales Forecast by Application (2022-2027) & (K Units) Table 66. Global Tracleer (bosentan) Sales Market Share Forecast by Application (2022-2027) Table 67. Global Tracleer (bosentan) Revenue Forecast by Application (2022-2027) & (US$ Million) Table 68. Global Tracleer (bosentan) Revenue Market Share Forecast by Application (2022-2027) Table 69. Global Tracleer (bosentan) Sales Forecast by Region (2022-2027) & (K Units) Table 70. Global Tracleer (bosentan) Sales Market Share Forecast by Region (2022-2027) Table 71. Global Tracleer (bosentan) Revenue Forecast by Region (2022-2027) & (US$ Million) Table 72. Global Tracleer (bosentan) Revenue Market Share Forecast by Region (2022-2027) Table 73. Research Programs/Design for This Report Table 74. Key Data Information from Secondary Sources Table 75. Key Data Information from Primary Sources List of Figures Figure 1. Product Picture of Tracleer (bosentan) Figure 2. Global Tracleer (bosentan) Market Share by Type in 2020 & 2027 Figure 3. 62.5 mg Tablet Product Picture Figure 4. 125 mg Tablet Product Picture Figure 5. Global Tracleer (bosentan) Market Share by Application in 2020 & 2027 Figure 6. Pediatric Patients Figure 7. Adult Patients Figure 8. Global Tracleer (bosentan) Revenue, (US$ Million), 2016 VS 2021 VS 2027 Figure 9. Global Tracleer (bosentan) Market Size 2016-2027 (US$ Million) Figure 10. Global Tracleer (bosentan) Sales 2016-2027 (K Units) Figure 11. Global Tracleer (bosentan) Market Size Market Share by Region: 2016 VS 20210 VS 2027 Figure 12. Tracleer (bosentan) Sales Share by Manufacturers in 2020 Figure 13. Global Tracleer (bosentan) Revenue Share by Manufacturers in 2020 Figure 14. The Global 5 and 10 Largest Tracleer (bosentan) Players: Market Share by Revenue in 2020 Figure 15. Tracleer (bosentan) Market Share by Company Type (Tier 1, Tier 2 and Tier 3): 2016 VS 2021 Figure 16. Global Tracleer (bosentan) Sales Market Share by Region (2016-2021) Figure 17. Global Tracleer (bosentan) Sales Market Share by Region in 2020 Figure 18. Global Tracleer (bosentan) Revenue Market Share by Region (2016-2021) Figure 19. Global Tracleer (bosentan) Revenue Market Share by Region in 2020 Figure 20. U.S. Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 21. Canada Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 22. Germany Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 23. France Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 24. U.K. Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 25. Italy Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 26. Russia Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 27. China Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 28. Japan Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 29. South Korea Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 30. India Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 31. Australia Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 32. Taiwan Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 33. Indonesia Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 34. Thailand Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 35. Malaysia Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 36. Philippines Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 37. Vietnam Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 38. Mexico Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 39. Brazil Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 40. Argentina Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 41. Turkey Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 42. Saudi Arabia Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 43. U.A.E Tracleer (bosentan) Revenue Growth Rate (2016-2021) (US$ Million) Figure 44. Sales Market Share of Tracleer (bosentan) by Type (2016-2021) Figure 45. Sales Market Share of Tracleer (bosentan) by Application (2016-2021) Figure 46. Sales Market Share of Tracleer (bosentan) by Application in 2020 Figure 47. Revenue Share of Tracleer (bosentan) by Application (2016-2021) Figure 48. Revenue Share of Tracleer (bosentan) by Application in 2020 Figure 49. Manufacturing Cost Structure of Tracleer (bosentan) Figure 50. Manufacturing Process Analysis of Tracleer (bosentan) Figure 51. Tracleer (bosentan) Industrial Chain Analysis Figure 52. Channels of Distribution Figure 53. Distributors Profiles Figure 54. Bottom-up and Top-down Approaches for This Report Figure 55. Data Triangulation Figure 56. Key Executives Interviewed

Actelion Pharmaceuticals