1 Study Coverage 1.1 Rectovaginal Fistula Revenue in Rectovaginal Fistula Business (2017-2022) & (US$ Million) Introduction 1.2 Global Rectovaginal Fistula Outlook 2017 VS 2022 VS 2028 1.2.1 Global Rectovaginal Fistula Market Size for the Year 2017-2028 1.2.2 Global Rectovaginal Fistula Market Size for the Year 2017-2028 1.3 Rectovaginal Fistula Market Size, United States VS Global, 2017 VS 2022 VS 2028 1.3.1 The Market Share of United States Rectovaginal Fistula in Global, 2017 VS 2022 VS 2028 1.3.2 The Growth Rate of Rectovaginal Fistula Market Size, United States VS Global, 2017 VS 2022 VS 2028 1.4 Rectovaginal Fistula Market Dynamics 1.4.1 Rectovaginal Fistula Industry Trends 1.4.2 Rectovaginal Fistula Market Drivers 1.4.3 Rectovaginal Fistula Market Challenges 1.4.4 Rectovaginal Fistula Market Restraints 1.5 Study Objectives 1.6 Years Considered 2 Rectovaginal Fistula by Type 2.1 Rectovaginal Fistula Market Segment by Type 2.1.1 Medicine 2.1.2 Surgery 2.1.3 Other 2.2 Global Rectovaginal Fistula Market Size by Type (2017, 2022 & 2028) 2.3 Global Rectovaginal Fistula Market Size by Type (2017-2028) 2.4 United States Rectovaginal Fistula Market Size by Type (2017, 2022 & 2028) 2.5 United States Rectovaginal Fistula Market Size by Type (2017-2028) 3 Rectovaginal Fistula by Application 3.1 Rectovaginal Fistula Market Segment by Application 3.1.1 Hospital 3.1.2 Clinic 3.1.3 Other 3.2 Global Rectovaginal Fistula Market Size by Application (2017, 2022 & 2028) 3.3 Global Rectovaginal Fistula Market Size by Application (2017-2028) 3.4 United States Rectovaginal Fistula Market Size by Application (2017, 2022 & 2028) 3.5 United States Rectovaginal Fistula Market Size by Application (2017-2028) 4 Global Rectovaginal Fistula Competitor Landscape by Company 4.1 Global Rectovaginal Fistula Market Size by Company 4.1.1 Top Global Rectovaginal Fistula Companies Ranked by Revenue (2021) 4.1.2 Global Rectovaginal Fistula Revenue by Player (2017-2022) 4.2 Global Rectovaginal Fistula Concentration Ratio (CR) 4.2.1 Rectovaginal Fistula Market Concentration Ratio (CR) (2017-2022) 4.2.2 Global Top 5 and Top 10 Largest Companies of Rectovaginal Fistula in 2021 4.2.3 Global Rectovaginal Fistula Market Share by Company Type (Tier 1, Tier 2, and Tier 3) 4.3 Global Rectovaginal Fistula Headquarters, Revenue in Rectovaginal Fistula Business (2017-2022) & (US$ Million) Type 4.3.1 Global Rectovaginal Fistula Headquarters and Area Served 4.3.2 Global Rectovaginal Fistula Companies Revenue in Rectovaginal Fistula Business (2017-2022) & (US$ Million) Type 4.3.3 Date of International Companies Enter into Rectovaginal Fistula Market 4.4 Companies Mergers & Acquisitions, Expansion Plans 4.5 United States Rectovaginal Fistula Market Size by Company 4.5.1 Top Rectovaginal Fistula Players in United States, Ranked by Revenue (2021) 4.5.2 United States Rectovaginal Fistula Revenue by Players (2020, 2021 & 2022) 5 Global Rectovaginal Fistula Market Size by Region 5.1 Global Rectovaginal Fistula Market Size by Region: 2017 VS 2022 VS 2028 5.2 Global Rectovaginal Fistula Market Size by Region (2017-2028) 5.2.1 Global Rectovaginal Fistula Market Size by Region: 2017-2022 5.2.2 Global Rectovaginal Fistula Market Size by Region (2023-2028) 6 Segment in Region Level & Country Level 6.1 North America 6.1.1 North America Rectovaginal Fistula Market Size YoY Growth 2017-2028 6.1.2 North America Rectovaginal Fistula Market Facts & Figures by Country (2017, 2022 & 2028) 6.1.3 U.S. 6.1.4 Canada 6.2 Asia-Pacific 6.2.1 Asia-Pacific Rectovaginal Fistula Market Size YoY Growth 2017-2028 6.2.2 Asia-Pacific Rectovaginal Fistula Market Facts & Figures by Region (2017, 2022 & 2028) 6.2.3 China 6.2.4 Japan 6.2.5 South Korea 6.2.6 India 6.2.7 Australia 6.2.8 Taiwan 6.2.9 Indonesia 6.2.10 Thailand 6.2.11 Malaysia 6.2.12 Philippines 6.3 Europe 6.3.1 Europe Rectovaginal Fistula Market Size YoY Growth 2017-2028 6.3.2 Europe Rectovaginal Fistula Market Facts & Figures by Country (2017, 2022 & 2028) 6.3.3 Germany 6.3.4 France 6.3.5 U.K. 6.3.6 Italy 6.3.7 Russia 6.4 Latin America 6.4.1 Latin America Rectovaginal Fistula Market Size YoY Growth 2017-2028 6.4.2 Latin America Rectovaginal Fistula Market Facts & Figures by Country (2017, 2022 & 2028) 6.4.3 Mexico 6.4.4 Brazil 6.4.5 Argentina 6.5 Middle East and Africa 6.5.1 Middle East and Africa Rectovaginal Fistula Market Size YoY Growth 2017-2028 6.5.2 Middle East and Africa Rectovaginal Fistula Market Facts & Figures by Country (2017, 2022 & 2028) 6.5.3 Turkey 6.5.4 Saudi Arabia 6.5.5 U.A.E 7 Company Profiles 7.1 Johnson & Johnson 7.1.1 Johnson & Johnson Company Details 7.1.2 Johnson & Johnson Business Overview 7.1.3 Johnson & Johnson Rectovaginal Fistula Introduction 7.1.4 Johnson & Johnson Revenue in Rectovaginal Fistula Business (2017-2022) 7.1.5 Johnson & Johnson Recent Development 7.2 Pfizer 7.2.1 Pfizer Company Details 7.2.2 Pfizer Business Overview 7.2.3 Pfizer Rectovaginal Fistula Introduction 7.2.4 Pfizer Revenue in Rectovaginal Fistula Business (2017-2022) 7.2.5 Pfizer Recent Development 7.3 Cook Medical 7.3.1 Cook Medical Company Details 7.3.2 Cook Medical Business Overview 7.3.3 Cook Medical Rectovaginal Fistula Introduction 7.3.4 Cook Medical Revenue in Rectovaginal Fistula Business (2017-2022) 7.3.5 Cook Medical Recent Development 7.4 Takeda Pharmaceutical 7.4.1 Takeda Pharmaceutical Company Details 7.4.2 Takeda Pharmaceutical Business Overview 7.4.3 Takeda Pharmaceutical Rectovaginal Fistula Introduction 7.4.4 Takeda Pharmaceutical Revenue in Rectovaginal Fistula Business (2017-2022) 7.4.5 Takeda Pharmaceutical Recent Development 7.5 Allergan 7.5.1 Allergan Company Details 7.5.2 Allergan Business Overview 7.5.3 Allergan Rectovaginal Fistula Introduction 7.5.4 Allergan Revenue in Rectovaginal Fistula Business (2017-2022) 7.5.5 Allergan Recent Development 7.6 Abbvie 7.6.1 Abbvie Company Details 7.6.2 Abbvie Business Overview 7.6.3 Abbvie Rectovaginal Fistula Introduction 7.6.4 Abbvie Revenue in Rectovaginal Fistula Business (2017-2022) 7.6.5 Abbvie Recent Development 7.7 Novartis International 7.7.1 Novartis International Company Details 7.7.2 Novartis International Business Overview 7.7.3 Novartis International Rectovaginal Fistula Introduction 7.7.4 Novartis International Revenue in Rectovaginal Fistula Business (2017-2022) 7.7.5 Novartis International Recent Development 7.8 Bayer 7.8.1 Bayer Company Details 7.8.2 Bayer Business Overview 7.8.3 Bayer Rectovaginal Fistula Introduction 7.8.4 Bayer Revenue in Rectovaginal Fistula Business (2017-2022) 7.8.5 Bayer Recent Development 7.9 Bristol-Myers Squibb 7.9.1 Bristol-Myers Squibb Company Details 7.9.2 Bristol-Myers Squibb Business Overview 7.9.3 Bristol-Myers Squibb Rectovaginal Fistula Introduction 7.9.4 Bristol-Myers Squibb Revenue in Rectovaginal Fistula Business (2017-2022) 7.9.5 Bristol-Myers Squibb Recent Development 7.10 Boehringer Ingelheim 7.10.1 Boehringer Ingelheim Company Details 7.10.2 Boehringer Ingelheim Business Overview 7.10.3 Boehringer Ingelheim Rectovaginal Fistula Introduction 7.10.4 Boehringer Ingelheim Revenue in Rectovaginal Fistula Business (2017-2022) 7.10.5 Boehringer Ingelheim Recent Development 7.11 F Hoffmann-La Roche 7.11.1 F Hoffmann-La Roche Company Details 7.11.2 F Hoffmann-La Roche Business Overview 7.11.3 F Hoffmann-La Roche Rectovaginal Fistula Introduction 7.11.4 F Hoffmann-La Roche Revenue in Rectovaginal Fistula Business (2017-2022) 7.11.5 F Hoffmann-La Roche Recent Development 7.12 Eli Lilly and Company 7.12.1 Eli Lilly and Company Company Details 7.12.2 Eli Lilly and Company Business Overview 7.12.3 Eli Lilly and Company Rectovaginal Fistula Introduction 7.12.4 Eli Lilly and Company Revenue in Rectovaginal Fistula Business (2017-2022) 7.12.5 Eli Lilly and Company Recent Development 7.13 GlaxoSmithkline 7.13.1 GlaxoSmithkline Company Details 7.13.2 GlaxoSmithkline Business Overview 7.13.3 GlaxoSmithkline Rectovaginal Fistula Introduction 7.13.4 GlaxoSmithkline Revenue in Rectovaginal Fistula Business (2017-2022) 7.13.5 GlaxoSmithkline Recent Development 7.14 Sanofi 7.14.1 Sanofi Company Details 7.14.2 Sanofi Business Overview 7.14.3 Sanofi Rectovaginal Fistula Introduction 7.14.4 Sanofi Revenue in Rectovaginal Fistula Business (2017-2022) 7.14.5 Sanofi Recent Development 8 Research Findings and Conclusion 9 Appendix 9.1 Research Methodology 9.1.1 Methodology/Research Approach 9.1.2 Data Source 9.2 Author Details 9.3 Disclaimer

List of Tables Table 1. Rectovaginal Fistula Market Size United States VS Global, CAGR (2017 VS 2022 VS 2028) Table 2. Rectovaginal Fistula Market Trends Table 3. Rectovaginal Fistula Market Drivers Table 4. Rectovaginal Fistula Market Challenges Table 5. Rectovaginal Fistula Market Restraints Table 6. Global Rectovaginal Fistula Market Size by Type: 2017 VS 2022 VS 2028 (US$ Million) Table 7. United States Rectovaginal Fistula Market Size by Type: 2017 VS 2022 VS 2028 (US$ Million) Table 8. Global Rectovaginal Fistula Market Size by Application: 2017 VS 2022 VS 2028 (US$ Million) Table 9. United States Rectovaginal Fistula Market Size by Application: 2017 VS 2022 VS 2028 (US$ Million) Table 10. Top Rectovaginal Fistula Companies in Global Market, Ranking by Revenue (2021) Table 11. Global Rectovaginal Fistula Revenue by Player, (US$ Million), 2017-2022 Table 12. Global Rectovaginal Fistula Revenue Share by Player, 2017-2022 Table 13. Global Rectovaginal Fistula Companies Market Concentration Ratio (CR5 and HHI) Table 14. Global Rectovaginal Fistula by Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in Rectovaginal Fistula as of 2021) Table 15. Top Players of Rectovaginal Fistula in Global Market, Headquarters and Area Served Table 16. Companies Revenue in Rectovaginal Fistula Business (2017-2022) & (US$ Million) Type Table 17. Date of International Companies Enter into Rectovaginal Fistula Market Table 18. Companies Mergers & Acquisitions, Expansion Plans Table 19. Top Rectovaginal Fistula Players in United States Market, Ranking by Revenue (2021) Table 20. United States Rectovaginal Fistula Revenue by Players, (US$ Million), 2020, 2021 & 2022 Table 21. United States Rectovaginal Fistula Revenue Share by Players, 2020, 2021 & 2022 Table 22. Global Rectovaginal Fistula Market Size by Region (US$ Million): 2017 VS 2022 VS 2028 Table 23. Global Rectovaginal Fistula Market Size by Region (2017-2022) & (US$ Million) Table 24. Global Rectovaginal Fistula Market Size Forecast by Region (2023-2028) & (US$ Million) Table 25. North America Rectovaginal Fistula Sales in Value by Country (2017-2028) & (US$ Million) Table 26. Asia Pacific Rectovaginal Fistula Sales in Value by Region (2017-2028) & (US$ Million) Table 27. Europe Rectovaginal Fistula Sales in Value by Country (2017-2028) & (US$ Million) Table 28. Latin Americaa Rectovaginal Fistula Sales in Value by Country (2017-2028) & (US$ Million) Table 29. Middle East and Africa Rectovaginal Fistula Sales in Value by Country (2017-2028) & (US$ Million) Table 30. Johnson & Johnson Company Details Table 31. Johnson & Johnson Business Overview Table 32. Johnson & Johnson Rectovaginal Fistula Product Table 33. Johnson & Johnson Revenue in Rectovaginal Fistula Business (2017-2022) & (US$ Million) Table 34. Johnson & Johnson Recent Development Table 35. Pfizer Company Details Table 36. Pfizer Business Overview Table 37. Pfizer Rectovaginal Fistula Product Table 38. Pfizer Revenue in Rectovaginal Fistula Business (2017-2022) & (US$ Million) Table 39. Pfizer Recent Development Table 40. Cook Medical Company Details Table 41. Cook Medical Business Overview Table 42. Cook Medical Rectovaginal Fistula Product Table 43. Cook Medical Revenue in Rectovaginal Fistula Business (2017-2022) & (US$ Million) Table 44. Cook Medical Recent Development Table 45. Takeda Pharmaceutical Company Details Table 46. Takeda Pharmaceutical Business Overview Table 47. Takeda Pharmaceutical Rectovaginal Fistula Product Table 48. Takeda Pharmaceutical Revenue in Rectovaginal Fistula Business (2017-2022) & (US$ Million) Table 49. Takeda Pharmaceutical Recent Development Table 50. Allergan Company Details Table 51. Allergan Business Overview Table 52. Allergan Rectovaginal Fistula Product Table 53. Allergan Revenue in Rectovaginal Fistula Business (2017-2022) & (US$ Million) Table 54. Allergan Recent Development Table 55. Abbvie Company Details Table 56. Abbvie Business Overview Table 57. Abbvie Rectovaginal Fistula Product Table 58. Abbvie Revenue in Rectovaginal Fistula Business (2017-2022) & (US$ Million) Table 59. Abbvie Recent Development Table 60. Novartis International Company Details Table 61. Novartis International Business Overview Table 62. Novartis International Rectovaginal Fistula Product Table 63. Novartis International Revenue in Rectovaginal Fistula Business (2017-2022) & (US$ Million) Table 64. Novartis International Recent Development Table 65. Bayer Company Details Table 66. Bayer Business Overview Table 67. Bayer Rectovaginal Fistula Product Table 68. Bayer Revenue in Rectovaginal Fistula Business (2017-2022) & (US$ Million) Table 69. Bayer Recent Development Table 70. Bristol-Myers Squibb Company Details Table 71. Bristol-Myers Squibb Business Overview Table 72. Bristol-Myers Squibb Rectovaginal Fistula Product Table 73. Bristol-Myers Squibb Revenue in Rectovaginal Fistula Business (2017-2022) & (US$ Million) Table 74. Bristol-Myers Squibb Recent Development Table 75. Boehringer Ingelheim Company Details Table 76. Boehringer Ingelheim Business Overview Table 77. Boehringer Ingelheim Rectovaginal Fistula Product Table 78. Boehringer Ingelheim Revenue in Rectovaginal Fistula Business (2017-2022) & (US$ Million) Table 79. Boehringer Ingelheim Recent Development Table 80. F Hoffmann-La Roche Company Details Table 81. F Hoffmann-La Roche Business Overview Table 82. F Hoffmann-La Roche Rectovaginal Fistula Product Table 83. F Hoffmann-La Roche Revenue in Rectovaginal Fistula Business (2017-2022) & (US$ Million) Table 84. F Hoffmann-La Roche Recent Development Table 85. Eli Lilly and Company Company Details Table 86. Eli Lilly and Company Business Overview Table 87. Eli Lilly and Company Rectovaginal Fistula Product Table 88. Eli Lilly and Company Revenue in Rectovaginal Fistula Business (2017-2022) & (US$ Million) Table 89. Eli Lilly and Company Recent Development Table 90. GlaxoSmithkline Company Details Table 91. GlaxoSmithkline Business Overview Table 92. GlaxoSmithkline Rectovaginal Fistula Product Table 93. GlaxoSmithkline Revenue in Rectovaginal Fistula Business (2017-2022) & (US$ Million) Table 94. GlaxoSmithkline Recent Development Table 95. Sanofi Company Details Table 96. Sanofi Business Overview Table 97. Sanofi Rectovaginal Fistula Product Table 98. Sanofi Revenue in Rectovaginal Fistula Business (2017-2022) & (US$ Million) Table 99. Sanofi Recent Development Table 100. Research Programs/Design for This Report Table 101. Key Data Information from Secondary Sources Table 102. Key Data Information from Primary Sources List of Figures Figure 1. Rectovaginal Fistula Product Picture Figure 2. Global Rectovaginal Fistula Market Size, (US$ Million), 2017 VS 2022 VS 2028 Figure 3. Global Rectovaginal Fistula Market Size 2017-2028 (US$ Million) Figure 4. United States Rectovaginal Fistula Market Size, (US$ Million), 2017 VS 2022 VS 2028 Figure 5. United States Rectovaginal Fistula Market Size 2017-2028 (US$ Million) Figure 6. United States Rectovaginal Fistula Market Share in Global 2017-2028 Figure 7. Rectovaginal Fistula Report Years Considered Figure 8. Product Picture of Medicine Figure 9. Product Picture of Surgery Figure 10. Product Picture of Other Figure 11. Global Rectovaginal Fistula Market Share by Type in 2022 & 2028 Figure 12. Global Rectovaginal Fistula Market Size by Type (2017-2028) & (US$ Million) Figure 13. Global Rectovaginal Fistula Market Share by Type (2017-2028) Figure 14. United States Rectovaginal Fistula Market Share by Type in 2022 & 2028 Figure 15. United States Rectovaginal Fistula Market Size by Type (2017-2028) & (US$ Million) Figure 16. United States Rectovaginal Fistula Market Share by Type (2017-2028) Figure 17. Product Picture of Hospital Figure 18. Product Picture of Clinic Figure 19. Product Picture of Other Figure 20. Global Rectovaginal Fistula Market Share by Application in 2022 & 2028 Figure 21. Global Rectovaginal Fistula Market Size by Application (2017-2028) & (US$ Million) Figure 22. Global Rectovaginal Fistula Market Share by Application (2017-2028) Figure 23. United States Rectovaginal Fistula Market Share by Application in 2022 & 2028 Figure 24. United States Rectovaginal Fistula Market Size by Application (2017-2028) & (US$ Million) Figure 25. United States Rectovaginal Fistula Market Share by Application (2017-2028) Figure 26. North America Rectovaginal Fistula Market Size Growth Rate 2017-2028 (US$ Million) Figure 27. U.S. Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 28. Canada Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 29. Europe Rectovaginal Fistula Market Size Growth Rate 2017-2028 (US$ Million) Figure 30. Germany Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 31. France Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 32. U.K. Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 33. Italy Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 34. Russia Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 35. Asia-Pacific Rectovaginal Fistula Market Size Growth Rate 2017-2028 (US$ Million) Figure 36. China Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 37. Japan Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 38. South Korea Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 39. India Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 40. Australia Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 41. Taiwan Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 42. Indonesia Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 43. Thailand Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 44. Malaysia Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 45. Philippines Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 46. Latin America Rectovaginal Fistula Market Size Growth Rate 2017-2028 (US$ Million) Figure 47. Mexico Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 48. Brazil Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 49. Argentina Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 50. Middle East & Africa Rectovaginal Fistula Market Size Growth Rate 2017-2028 (US$ Million) Figure 51. Turkey Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 52. Saudi Arabia Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 53. U.A.E Rectovaginal Fistula Market Size Growth Rate (2017-2028) & (US$ Million) Figure 54. Johnson & Johnson Revenue Growth Rate in Rectovaginal Fistula Business (2017-2022) Figure 55. Pfizer Revenue Growth Rate in Rectovaginal Fistula Business (2017-2022) Figure 56. Cook Medical Revenue Growth Rate in Rectovaginal Fistula Business (2017-2022) Figure 57. Takeda Pharmaceutical Revenue Growth Rate in Rectovaginal Fistula Business (2017-2022) Figure 58. Allergan Revenue Growth Rate in Rectovaginal Fistula Business (2017-2022) Figure 59. Abbvie Revenue Growth Rate in Rectovaginal Fistula Business (2017-2022) Figure 60. Novartis International Revenue Growth Rate in Rectovaginal Fistula Business (2017-2022) Figure 61. Bayer Revenue Growth Rate in Rectovaginal Fistula Business (2017-2022) Figure 62. Bristol-Myers Squibb Revenue Growth Rate in Rectovaginal Fistula Business (2017-2022) Figure 63. Boehringer Ingelheim Revenue Growth Rate in Rectovaginal Fistula Business (2017-2022) Figure 64. F Hoffmann-La Roche Revenue Growth Rate in Rectovaginal Fistula Business (2017-2022) Figure 65. Eli Lilly and Company Revenue Growth Rate in Rectovaginal Fistula Business (2017-2022) Figure 66. GlaxoSmithkline Revenue Growth Rate in Rectovaginal Fistula Business (2017-2022) Figure 67. Sanofi Revenue Growth Rate in Rectovaginal Fistula Business (2017-2022) Figure 68. Bottom-up and Top-down Approaches for This Report Figure 69. Data Triangulation Figure 70. Key Executives Interviewed

Johnson & Johnson Pfizer Cook Medical Takeda Pharmaceutical Allergan Abbvie Novartis International Bayer Bristol-Myers Squibb Boehringer Ingelheim F Hoffmann-La Roche Eli Lilly and Company GlaxoSmithkline Sanofi